1,2-Propanediol, 3-(dodecyloxy)-, (R)-

Base Information

Chemical Name:1,2-Propanediol, 3-(dodecyloxy)-, (R)-
CAS No.:90904-23-7
Molecular Formula:C15H32O3
Molecular Weight:260.41300
Hs Code.:

Synonyms:(-)-3-dodecyloxy-propane-1,2-diol;(-)-3-Dodecyloxy-propan-1,2-diol;(-)-O1-Dodecyl-glycerin;3-O-dodecyl-sn-glycerol;(R)-3-Dodecyloxy-propane-1,2-diol;

Suppliers and Price of 1,2-Propanediol, 3-(dodecyloxy)-, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-O-Dodecyl-sn-glycerol
1g
$ 540.00

TRC
3-O-Dodecyl-sn-glycerol
100mg
$ 115.00

Total 0 raw suppliers

Chemical Property of 1,2-Propanediol, 3-(dodecyloxy)-, (R)-

Chemical Property:

Boiling Point:390.5±22.0 °C(Predicted)
PSA：49.69000
Density:0.937±0.06 g/cm3(Predicted)
LogP:3.27710

Purity/Quality:: 3-O-Dodecyl-sn-glycerol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3-O-Dodecyl-sn-glycerol is used in the preparation of cysteine based lipopeptides and compositions as TLR2 agonists useful for treating infections, inflammations, respiratory, dermatological and autoimmune diseases.

Technology Process of 1,2-Propanediol, 3-(dodecyloxy)-, (R)-

There total 5 articles about 1,2-Propanediol, 3-(dodecyloxy)-, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 478549-98-3
3-O-dodecyl-1,2-O-isopropylidene-sn-glycerol

: 90904-23-7,1561-07-5
3-O-dodecyl-sn-glycerol

Guidance literature:: With 80percent aq. AcOH; at 20 ℃;
DOI:10.1021/ja020396+

Reference yield: 31.8%

: 112-53-8
1-dodecyl alcohol

: 57044-25-4
(R)-oxiranemethanol

: 90904-23-7,1561-07-5
3-O-dodecyl-sn-glycerol

Guidance literature:: 1-dodecyl alcohol; With diisobutylaluminium hydride; In hexane; dichloromethane; for 1h; Cooling with ice;

(R)-oxiranemethanol; In hexane; dichloromethane; at 20 ℃; for 72h;

With water; Rochelle's salt; In hexane; dichloromethane; for 0.5h;
DOI:10.1016/j.bmc.2009.03.030

Reference yield:

: 143-15-7
1-dodecylbromide

: 90904-23-7,1561-07-5
3-O-dodecyl-sn-glycerol

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / 50percent aq. NaOH; tetrabutylammonium bromide / 20 h / 80 °C

2: 99 percent / 80percent aq. AcOH / 20 °C

With tetrabutylammomium bromide;
DOI:10.1021/ja020396+