Methyl 2-benzoyl-4-hydroxy-5-iodo-3-methyl-1,2-oxazinane-6-carboxylate

Base Information

Chemical Name:Methyl 2-benzoyl-4-hydroxy-5-iodo-3-methyl-1,2-oxazinane-6-carboxylate
CAS No.:92254-85-8
Molecular Formula:C14H16INO5
Molecular Weight:405.185
Hs Code.:
NSC Number:173133
DSSTox Substance ID:DTXSID10306000

Synonyms:92254-85-8;NSC173133;DTXSID10306000;NSC-173133;methyl 2-benzoyl-4-hydroxy-5-iodo-3-methyl-1,2-oxazinane-6-carboxylate

Suppliers and Price of Methyl 2-benzoyl-4-hydroxy-5-iodo-3-methyl-1,2-oxazinane-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Methyl 2-benzoyl-4-hydroxy-5-iodo-3-methyl-1,2-oxazinane-6-carboxylate

Chemical Property:

Vapor Pressure:1.4E-11mmHg at 25°C
Boiling Point:518.5°Cat760mmHg
Flash Point:267.4°C
Density:1.72g/cm³
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:405.00732
Heavy Atom Count:21
Complexity:399

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C(C(C(ON1C(=O)C2=CC=CC=C2)C(=O)OC)I)O

Technology Process of Methyl 2-benzoyl-4-hydroxy-5-iodo-3-methyl-1,2-oxazinane-6-carboxylate

There total 4 articles about Methyl 2-benzoyl-4-hydroxy-5-iodo-3-methyl-1,2-oxazinane-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 689-89-4
(2E,4E)-methylhexa-2,4-dienoate

: 92254-85-8
2-benzoyl-4c-hydroxy-5t-iodo-3c-methyl-[1,2]oxazinane-6r-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: diethyl ether; ethanol / 336 h / 0 °C

2: aq. NaHCO₃

3: (i) Na₂HPO₄, ClCH₂CH₂Cl, (ii) H₂O₂, ClCH₂CH₂Cl, (CF₃CO)2O

4: aq. HCl

With hydrogenchloride; sodium hydrogencarbonate; In diethyl ether; ethanol;
DOI:10.1021/ja00884a013

Reference yield:

: 92961-63-2
2-benzoyl-4c,5c-epoxy-3c-methyl-[1,2]oxazinane-6r-carboxylic acid methyl ester

: 92254-85-8
2-benzoyl-4c-hydroxy-5t-iodo-3c-methyl-[1,2]oxazinane-6r-carboxylic acid methyl ester

Guidance literature:: With hydrogenchloride;
DOI:10.1021/ja00884a013

Reference yield:

: 412338-32-0
3,6-dihydro-6-methoxycarbonyl-3-methyl-2H-1,2-oxazine

: 92254-85-8
2-benzoyl-4c-hydroxy-5t-iodo-3c-methyl-[1,2]oxazinane-6r-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaHCO₃

2: (i) Na₂HPO₄, ClCH₂CH₂Cl, (ii) H₂O₂, ClCH₂CH₂Cl, (CF₃CO)2O

3: aq. HCl

With hydrogenchloride; sodium hydrogencarbonate;
DOI:10.1021/ja00884a013