3-ETHOXY BENZALDEHYDE OXIME

Base Information

• Chemical Name: 3-ETHOXY BENZALDEHYDE OXIME
• CAS No.: 90943-37-6
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Mol file: 90943-37-6.mol

Synonyms:3-Ethoxy-benzaldehyd-oxim;Benzaldehyde,3-ethoxy-,oxime;3-ethoxybenzaldoxime;

Chemical Property of 3-ETHOXY BENZALDEHYDE OXIME

Chemical Property:

• PSA: 41.82000
• LogP: 1.89340

Purity/Quality:

3-ETHOXYBENZALDEHYDEOXIME 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-ETHOXY BENZALDEHYDE OXIME

There total 2 articles about 3-ETHOXY BENZALDEHYDE OXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3-ethoxybenzaldehyde (22924-15-8) → 3-ethoxybenzaldoxime (90943-37-6)

Guidance literature:

With hydroxylamine hydrochloride; potassium carbonate; In water; Reflux;

DOI:10.2174/1570180816666181227115738

Reference yield:

meta-hydroxybenzaldehyde (100-83-4) → 3-ethoxybenzaldoxime (90943-37-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / acetone / Heating

2: (NH₂OH)2*H₂SO₄; sodium acetate / ethanol / Heating

With hydroxyammonium sulfate; sodium acetate; In ethanol; acetone;

DOI:10.1016/j.bmc.2005.04.075

Reference yield: 65.0%

3-ethoxybenzaldoxime (90943-37-6) + 2,6-difluoro-3-(prop-2-yn-1-yloxy)benzamide → 3-((3-(3-ethoxyphenyl)isoxazol-5-yl)methoxy)-2,6-difluorobenzamide

Guidance literature:

With chloroamine-T; In ethanol; water; at 20 ℃;

DOI:10.1016/j.ejmech.2018.09.053

upstream raw materials:

3-ethoxybenzaldehyde

meta-hydroxybenzaldehyde

Downstream raw materials:

3-(ethyloxy)benzonitrile

Refernces

• 1、 Song, Di,Bi, Fangchao,Zhang, Nan,Qin, Yinhui,Liu, Xingbang,Teng, Yuetai,Ma, Shutao. "Design, synthesis of novel 4,5-dihydroisoxazole-containing benzamide derivatives as highly potent FtsZ inhibitors capable of killing a variety of MDR Staphylococcus aureus". supporting information. . Retrieved 2020/09/11.
• 2、 Master, Hoshang E.,Khan, Shabana I.,Poojari, Krishna A.. "Design and synthesis of low molecular weight compounds with complement inhibition activity". . p. 4891 - 4899. Retrieved 2007/10/03.