2-(4-Bromophenyl)-5-propyloxan-2-ol

Base Information

Chemical Name:2-(4-Bromophenyl)-5-propyloxan-2-ol
CAS No.:911142-61-5
Molecular Formula:C14H19BrO2
Molecular Weight:299.208
Hs Code.:
DSSTox Substance ID:DTXSID10582049
Nikkaji Number:J2.613.936H

Synonyms:911142-61-5;2-(4-Bromophenyl)-5-propyloxan-2-ol;SCHEMBL5160908;DTXSID10582049

Suppliers and Price of 2-(4-Bromophenyl)-5-propyloxan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Bromophenyl)-5-propyloxan-2-ol

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:298.05684
Heavy Atom Count:17
Complexity:238

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1CCC(OC1)(C2=CC=C(C=C2)Br)O

Technology Process of 2-(4-Bromophenyl)-5-propyloxan-2-ol

There total 5 articles about 2-(4-Bromophenyl)-5-propyloxan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: [1-(4-Bromo-phenyl)-eth-(Z)-ylidene]-cyclohexyl-amine

: 10317-18-7
3-propyloxetane

: 911142-61-5
2-(4-bromo-phenyl)-5-propyl-tetrahydro-pyran-2-ol

Guidance literature:: [1-(4-Bromo-phenyl)-eth-(Z)-ylidene]-cyclohexyl-amine; With 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; hexane; at -70 - -60 ℃; for 0.666667h;

3-propyloxetane; With boron trifluoride diethyl etherate; In tetrahydrofuran; hexane; at 20 ℃; for 10h;
DOI:10.1002/ejoc.200600160

Reference yield:

: 106-37-6
1.4-dibromobenzene

: 214335-70-3
tetrahydro-5-propyl-2H-pyran-2-one

: 911142-61-5
2-(4-bromo-phenyl)-5-propyl-tetrahydro-pyran-2-ol

Guidance literature:: With n-butyllithium; In diethyl ether; hexane; at -50 - 0 ℃; for 1.5h;
DOI:10.1002/ejoc.200800149

Reference yield:

: 2612-28-4
2-propyl-propane-1,3-diol

: 911142-61-5
2-(4-bromo-phenyl)-5-propyl-tetrahydro-pyran-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: 65 percent / bromine; PPh₃; pyridine / CH₂Cl₂ / 18 h / 20 °C

2.1: 86 percent / Bu₃SnOMe / 50 °C / 75.01 Torr

3.1: lithium 2,2,6,6-tetramethylpiperidine / tetrahydrofuran; hexane / 0.67 h / -70 - -60 °C

3.2: 74 percent / BF₃*OEt₂ / tetrahydrofuran; hexane / 10 h / 20 °C

With pyridine; 2,2,6,6-tetramethylpiperidinyl-lithium; bromine; tributyltin methoxide; triphenylphosphine; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1002/ejoc.200600160