2-(2-Propynylthio)ethylamine

Base Information

• Chemical Name: 2-(2-Propynylthio)ethylamine
• CAS No.: 75606-28-9
• Molecular Formula: C5H9NS
• Molecular Weight: 115.199
• Mol file: 75606-28-9.mol

Synonyms:S-propargyl-2-aminoethanethiol;

Chemical Property of 2-(2-Propynylthio)ethylamine

Chemical Property:

• Vapor Pressure: 0.448mmHg at 25°C
• Boiling Point: 194.2°Cat760mmHg
• Flash Point: 71.2°C
• PSA: 51.32000
• Density: 1.024g/cm³
• LogP: 1.01180

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-Propynylthio)ethylamine

There total 2 articles about 2-(2-Propynylthio)ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

bromoethyne (593-61-3) + Cysteamine (60-23-1) → S-propargyl-2-aminoethanethiol (75606-28-9)

Guidance literature:

In 1,4-dioxane; at 60 - 70 ℃; for 3h;

Reference yield:

S-propargyl-2-aminoethanethiol TFA salt → S-propargyl-2-aminoethanethiol (75606-28-9)

Guidance literature:

With sodium hydroxide; In water;

DOI:10.1002/chem.200702024

Reference yield: 77.0%

S-propargyl-2-aminoethanethiol (75606-28-9) + C8H8BrClS → C13H16ClNS2

Guidance literature:

With potassium carbonate; In acetone; for 7h; Reflux;

upstream raw materials:

bromoethyne

Cysteamine

Refernces

• 1、 Mesnard,Miginiac,Fatome,et al.. "Synthesis and radiopharmacological study of unsaturated derivatives of cysteamine". . p. 247 - 252. Retrieved 2007/10/02.