5-Phenyl-3-(2-((trimethylsilyl)oxy)propan-2-yl)-4,5-dihydroisoxazole

Base Information

Chemical Name:5-Phenyl-3-(2-((trimethylsilyl)oxy)propan-2-yl)-4,5-dihydroisoxazole
CAS No.:91157-63-0
Molecular Formula:C15H23NO2Si
Molecular Weight:277.439
Hs Code.:
DSSTox Substance ID:DTXSID30535698

Synonyms:91157-63-0;5-Phenyl-3-(2-((trimethylsilyl)oxy)propan-2-yl)-4,5-dihydroisoxazole;DTXSID30535698;5-Phenyl-3-{2-[(trimethylsilyl)oxy]propan-2-yl}-4,5-dihydro-1,2-oxazole

Suppliers and Price of 5-Phenyl-3-(2-((trimethylsilyl)oxy)propan-2-yl)-4,5-dihydroisoxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-Phenyl-3-(2-((trimethylsilyl)oxy)propan-2-yl)-4,5-dihydroisoxazole

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:277.149805511
Heavy Atom Count:19
Complexity:341

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C1=NOC(C1)C2=CC=CC=C2)O[Si](C)(C)C

Technology Process of 5-Phenyl-3-(2-((trimethylsilyl)oxy)propan-2-yl)-4,5-dihydroisoxazole

There total 3 articles about 5-Phenyl-3-(2-((trimethylsilyl)oxy)propan-2-yl)-4,5-dihydroisoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6
styrene

: 55816-65-4
2-<(Trimethylsilyl)oxy>-2-methyl-1-nitropropane

: 91157-63-0
5-Phenyl-3-<1-<(trimethylsilyl)oxy>-1-methyl-ethyl>-Δ²-isoxazoline

Guidance literature:: With phenyl isocyanate; triethylamine; In benzene; for 20h; Heating;
DOI:10.1021/jo00193a008

Reference yield: 63.0%

: 100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6
styrene

: 98269-77-3
bis<2-<(trimethylsilyl)-oxy>prop-2-yl>furoxan

: 91157-63-0
5-Phenyl-3-<1-<(trimethylsilyl)oxy>-1-methyl-ethyl>-Δ²-isoxazoline

Guidance literature:: In benzene; at 165 ℃; for 17h; Heating;
DOI:10.1021/ja00307a031

Reference yield:

: 55816-65-4
2-<(Trimethylsilyl)oxy>-2-methyl-1-nitropropane

: 91157-63-0
5-Phenyl-3-<1-<(trimethylsilyl)oxy>-1-methyl-ethyl>-Δ²-isoxazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / triethylamine / benzene / 18 h / Heating

2: 63 percent / benzene / 17 h / 165 °C / Heating

With triethylamine; In benzene;
DOI:10.1021/ja00307a031