3-[4-(3-Hydroxyprop-1-ynyl)phenyl]prop-2-yn-1-ol

Base Information

Chemical Name:3-[4-(3-Hydroxyprop-1-ynyl)phenyl]prop-2-yn-1-ol
CAS No.:91207-12-4
Molecular Formula:C12H10O2
Molecular Weight:186.21
Hs Code.:
DSSTox Substance ID:DTXSID00532134
Nikkaji Number:J2.678.590A
Wikidata:Q82404510

Synonyms:91207-12-4;3-[4-(3-Hydroxyprop-1-ynyl)phenyl]prop-2-yn-1-ol;SCHEMBL6446069;DTXSID00532134;OZNNCQSFOZPYEM-UHFFFAOYSA-N;1,4-bis-(3-hydroxyprop-1-ynyl)-benzene;3,3'-(1,4-Phenylene)di(prop-2-yn-1-ol);3-[4-(3-Hydroxy-prop-1-ynyl)-phenyl]-prop-2-yn-1-ol

Suppliers and Price of 3-[4-(3-Hydroxyprop-1-ynyl)phenyl]prop-2-yn-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-[4-(3-Hydroxyprop-1-ynyl)phenyl]prop-2-yn-1-ol

Chemical Property:

PSA：40.46000
LogP:0.37420
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:186.068079557
Heavy Atom Count:14
Complexity:253

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C#CCO)C#CCO

Technology Process of 3-[4-(3-Hydroxyprop-1-ynyl)phenyl]prop-2-yn-1-ol

There total 4 articles about 3-[4-(3-Hydroxyprop-1-ynyl)phenyl]prop-2-yn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 624-38-4,1032416-46-8
para-diiodobenzene

: 107-19-7
propargyl alcohol

: 91207-12-4
3,3’-(1,4-phenylene)bis(prop-2-yn-1-ol)

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; at 20 ℃; for 10h; Inert atmosphere;
DOI:10.1021/jacs.1c06732

Reference yield: 95.0%

: 106-37-6
1.4-dibromobenzene

: 107-19-7
propargyl alcohol

: 91207-12-4
3,3’-(1,4-phenylene)bis(prop-2-yn-1-ol)

Guidance literature:: With propylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 60 ℃; Inert atmosphere;
DOI:10.1002/anie.201701524

Reference yield: 82.0%

: 19070-80-5
n-<(trimethylsiloxy)methyl>phthalimide

: 17938-13-5
1,4-Bis(trimethylsilylethynyl)benzene

: 91207-12-4
3,3’-(1,4-phenylene)bis(prop-2-yn-1-ol)

Guidance literature:: n-<(trimethylsiloxy)methyl>phthalimide; 1,4-Bis(trimethylsilylethynyl)benzene; With sodium phenoxide; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

With potassium carbonate; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/ejoc.201701440