4-Ethoxynaphthalene-1-sulfonyl chloride

Base Information

• Chemical Name: 4-Ethoxynaphthalene-1-sulfonyl chloride
• CAS No.: 91222-55-8
• Molecular Formula: C12H11ClO3S
• Molecular Weight: 270.73200
• European Community (EC) Number: 819-146-9
• DSSTox Substance ID: DTXSID10588203
• Wikidata: Q82480727
• Mol file: 91222-55-8.mol

Synonyms:4-ethoxynaphthalene-1-sulfonyl chloride;91222-55-8;4-ETHOXY-1-NAPHTHALENESULFONYL CHLORIDE;4-Ethoxynaphthalene-1-sulfonylchloride;SCHEMBL3759669;DTXSID10588203;MFCD09044337;AKOS000128082;AT25707;BS-38675;DB-340257;CS-0250847;EN300-52432;4-ethoxynaphthalene-1-sulfonyl chloride, AldrichCPR;4-ethoxy-1-naphthalenesulfonyl chloride(SALTDATA: FREE)

Chemical Property of 4-Ethoxynaphthalene-1-sulfonyl chloride

Chemical Property:

• PSA: 51.75000
• LogP: 4.24680
• Storage Temp.: 2-8°C
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 270.0117431
• Heavy Atom Count: 17
• Complexity: 349

Purity/Quality:

98% ^*data from raw suppliers

4-Ethoxynaphthalene-1-sulfonyl chloride 95+% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC=C(C2=CC=CC=C21)S(=O)(=O)Cl

Technology Process of 4-Ethoxynaphthalene-1-sulfonyl chloride

There total 3 articles about 4-Ethoxynaphthalene-1-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H11O4S(1-)*Na(1+) → 4-ethoxy-naphthalene-1-sulfonyl chloride (91222-55-8)

Guidance literature:

With thionyl chloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h;

DOI:10.1016/j.bmc.2019.07.031

Reference yield:

sodium 1-naphthol-4-sulfonate (6099-57-6) → 4-ethoxy-naphthalene-1-sulfonyl chloride (91222-55-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol; water / 80 °C / Sealed tube

2: thionyl chloride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C

With thionyl chloride; sodium hydroxide; In ethanol; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2019.07.031

Reference yield:

→ 4-ethoxy-naphthalene-1-sulfonyl chloride (91222-55-8)

Guidance literature:

With phosphorus pentachloride;

upstream raw materials:

sodium 1-naphthol-4-sulfonate

Refernces