2-(Aminomethyl)-6-tert-butyl-4-methylphenol

Base Information

Chemical Name:2-(Aminomethyl)-6-tert-butyl-4-methylphenol
CAS No.:91432-09-6
Molecular Formula:C12H19NO
Molecular Weight:193.289
Hs Code.:
ChEMBL ID:CHEMBL1194119
DSSTox Substance ID:DTXSID70505759
Wikidata:Q82361059

Synonyms:2-(aminomethyl)-6-tert-butyl-4-methylphenol;91432-09-6;SCHEMBL8747636;CHEMBL1194119;DTXSID70505759;2-hydroxy-3-t-butyl-5-methylbenzylamine

Suppliers and Price of 2-(Aminomethyl)-6-tert-butyl-4-methylphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(Aminomethyl)-6-tert-butyl-4-methylphenol

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:193.146664230
Heavy Atom Count:14
Complexity:185

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C(C)(C)C)O)CN

Technology Process of 2-(Aminomethyl)-6-tert-butyl-4-methylphenol

There total 2 articles about 2-(Aminomethyl)-6-tert-butyl-4-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 49592-92-9
3-tert-butyl-2-hydroxy-5-methylbenzyl chloride

: 91432-09-6
(3-tert-butyl-2-hydroxy-5-methylbenzyl)amine

Guidance literature:: 3-tert-butyl-2-hydroxy-5-methylbenzyl chloride; With chloro-trimethyl-silane; triethylamine; In toluene; at 20 ℃; for 1.5h; Inert atmosphere;

With lithium hexamethyldisilazane; In toluene; at -78 - 20 ℃; for 17h; Inert atmosphere;
DOI:10.1007/s11172-021-3222-3

Reference yield:

: 2409-55-4
2-tert-Butyl-4-methylphenol

: 91432-09-6
(3-tert-butyl-2-hydroxy-5-methylbenzyl)amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / toluene / 2 h / -5 - 20 °C

2.1: chloro-trimethyl-silane; triethylamine / toluene / 1.5 h / 20 °C / Inert atmosphere

2.2: 17 h / -78 - 20 °C / Inert atmosphere

With hydrogenchloride; chloro-trimethyl-silane; triethylamine; In toluene;
DOI:10.1007/s11172-021-3222-3