Indole, 5-methoxy-3-(4-piperidylmethyl)-

Base Information

Chemical Name:Indole, 5-methoxy-3-(4-piperidylmethyl)-
CAS No.:3515-52-4
Molecular Formula:C15H20N2O
Molecular Weight:244.3321
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10188646
Wikidata:Q83060461
ChEMBL ID:CHEMBL24075
Mol file:3515-52-4.mol

Synonyms:BRN 0749828;3515-52-4;INDOLE, 5-METHOXY-3-(4-PIPERIDYLMETHYL)-;5-Methoxy-3-(4-piperidinomethyl)indole;CHEMBL24075;5-Methoxy-3-(4-piperidinylmethyl)-1H-indole;SCHEMBL10956998;DTXSID10188646;URURNXZHHMVWSK-UHFFFAOYSA-N;BDBM50029155;LS-83234;5-Methoxy-3-piperidin-4-ylmethyl-1H-indole;4-[(5-methoxy-3-indolyl)-methyl]-piperidine

Suppliers and Price of Indole, 5-methoxy-3-(4-piperidylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Indole, 5-methoxy-3-(4-piperidylmethyl)-

Chemical Property:

Vapor Pressure:8.28E-08mmHg at 25°C
Melting Point:152-153 °C
Boiling Point:436.1°Cat760mmHg
PKA:17.00±0.30(Predicted)
Flash Point:217.6°C
PSA：37.05000
Density:1.124g/cm³
LogP:3.04740
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:244.157563266
Heavy Atom Count:18
Complexity:265

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)NC=C2CC3CCNCC3

Technology Process of Indole, 5-methoxy-3-(4-piperidylmethyl)-

There total 3 articles about Indole, 5-methoxy-3-(4-piperidylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 75259-75-5
(5-Methoxy-1H-indol-3-yl)-piperidin-4-yl-methanone; hydrochloride

: 3515-52-4
5-Methoxy-3-<4>piperidylmethyl-indol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; 1.) 20 deg C, 3 h, 2.) reflux, 15 min;
DOI:10.1021/jm00186a005

Reference yield:

: 4-(5-Methoxy-1H-indole-3-carbonyl)-piperidine-1-carboxylic acid benzyl ester

: 3515-52-4
5-Methoxy-3-<4>piperidylmethyl-indol

Guidance literature:: Multi-step reaction with 2 steps

1: 5 N HCl / ethanol / 4 h / Heating

2: 38 percent / LiAlH₄ / tetrahydrofuran / 1.) 20 deg C, 3 h, 2.) reflux, 15 min

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00186a005

Reference yield:

: 3515-52-4
5-Methoxy-3-<4>piperidylmethyl-indol

Guidance literature:: 1-Acetyl-5-methoxy-3-<4>pyridylmethyl-oxindol, 1. Pt, wss.-aethanol. HCl, Hydrierung (bis zur Aufnahme von 3 Mol H2), 2. sd. Propan-1-ol, Na;