1-Bromo-2-diethoxyphosphorylbenzene

Base Information

Chemical Name:1-Bromo-2-diethoxyphosphorylbenzene
CAS No.:77526-90-0
Molecular Formula:C10H14 Br O3 P
Molecular Weight:293.097
Hs Code.:
NSC Number:141168
DSSTox Substance ID:DTXSID80301108
Nikkaji Number:J3.505.907E
Wikidata:Q82044690

Synonyms:77526-90-0;diethyl (2-bromophenyl)phosphonate;1-bromo-2-diethoxyphosphorylbenzene;NSC141168;SCHEMBL6839385;DTXSID80301108;NSC-141168;SY311557

Suppliers and Price of 1-Bromo-2-diethoxyphosphorylbenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Bromo-2-diethoxyphosphorylbenzene

Chemical Property:

Vapor Pressure:0.000266mmHg at 25°C
Boiling Point:333.4°Cat760mmHg
Flash Point:155.4°C
Density:1.41g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:291.98639
Heavy Atom Count:15
Complexity:225

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C1=CC=CC=C1Br)OCC

Technology Process of 1-Bromo-2-diethoxyphosphorylbenzene

There total 5 articles about 1-Bromo-2-diethoxyphosphorylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 762-04-9
phosphonic acid diethyl ester

: 244205-40-1
(2-bromophenyl)boronic acid

: 77526-90-0
diethyl (2-bromobenzyl)phosphonate

Guidance literature:: With copper(I) oxide; 1,10-Phenanthroline; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃;
DOI:10.1021/jacs.0c04159

Reference yield: 74.0%

: 583-55-1
1-Bromo-2-iodobenzene

: 762-04-9
phosphonic acid diethyl ester

: 77526-90-0
diethyl (2-bromobenzyl)phosphonate

Guidance literature:: With diisopropylamine; triphenylphosphine; palladium diacetate; In ethanol; for 48h; Heating;
DOI:10.1021/jo800969x

Reference yield: 62.0%

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 122-52-1
triethyl phosphite

: 77526-90-0
diethyl (2-bromobenzyl)phosphonate

Guidance literature:: With potassium fluoride; 18-crown-6 ether; Bromoform; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 65 ℃; for 24h; Molecular sieve;
DOI:10.1021/acs.joc.1c00550