Technology Process of 2-Oxazolepropanoic acid, b-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-,
methyl ester
There total 3 articles about 2-Oxazolepropanoic acid, b-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-,
methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium on activated charcoal; hydrogen;
In
methanol;
at 20 ℃;
for 0.5h;
Inert atmosphere;
DOI:10.1021/ml400501x
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.33 h / -78 °C / Inert atmosphere
1.2: 1.5 h / -78 °C / Inert atmosphere
2.1: palladium on activated charcoal; hydrogen / methanol / 0.5 h / 20 °C / Inert atmosphere
With
palladium on activated charcoal; hydrogen; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol;
DOI:10.1021/ml400501x
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: pyridinium chlorochromate / dichloromethane / 1 h / Inert atmosphere
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.33 h / -78 °C / Inert atmosphere
2.2: 1.5 h / -78 °C / Inert atmosphere
3.1: palladium on activated charcoal; hydrogen / methanol / 0.5 h / 20 °C / Inert atmosphere
With
palladium on activated charcoal; hydrogen; pyridinium chlorochromate; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ml400501x
