Triethyl 1,3-difluoro-2-hydroxypropane-1,2,3-tricarboxylate

Base Information

Chemical Name:Triethyl 1,3-difluoro-2-hydroxypropane-1,2,3-tricarboxylate
CAS No.:2728-90-7
Molecular Formula:C12H18 F2 O7
Molecular Weight:312.268
Hs Code.:2918199090
European Community (EC) Number:220-343-1
DSSTox Substance ID:DTXSID10950007
Nikkaji Number:J299.199C
Mol file:2728-90-7.mol

Synonyms:2728-90-7;Triethyl 1,3-difluoro-2-hydroxypropane-1,2,3-tricarboxylate;EINECS 220-343-1;1,5-diethyl 2,4-dideoxy-3-c-(ethoxycarbonyl)-2,4-difluoropentarate;DTXSID10950007;C12H18F2O7;C12-H18-F2-O7;1,3-Difluoro-2-hydroxy-1,2,3-propanetricarboxylic acid triethyl ester

Suppliers and Price of Triethyl 1,3-difluoro-2-hydroxypropane-1,2,3-tricarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Triethyl 1,3-difluoro-2-hydroxypropane-1,2,3-tricarboxylate

Chemical Property:

Vapor Pressure:6.4E-08mmHg at 25°C
Melting Point:68 °C
Boiling Point:396.2°Cat760mmHg
PKA:9.50±0.29(Predicted)
Flash Point:193.4°C
PSA：99.13000
Density:1.267g/cm³
LogP:0.08300
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:11
Exact Mass:312.10205923
Heavy Atom Count:21
Complexity:362

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C(C(C(=O)OCC)F)(C(=O)OCC)O)F

Technology Process of Triethyl 1,3-difluoro-2-hydroxypropane-1,2,3-tricarboxylate

There total 2 articles about Triethyl 1,3-difluoro-2-hydroxypropane-1,2,3-tricarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.4%

: 459-72-3
ethyl 2-fluoroacetate

: 95-92-1
oxalic acid diethyl ester

: 392-58-5
Diethyl fluoroxaloacetate

: 2728-90-7
α,α'-difluorocitric triethyl ester

Guidance literature:: oxalic acid diethyl ester; With sodium ethanolate; In ethanol; for 0.25h; Cooling with ice;

ethyl 2-fluoroacetate; In ethanol; at 20 ℃; Cooling with ice;
DOI:10.1016/j.jfluchem.2011.07.006