Diflumidone

Base Information

Chemical Name:Diflumidone
CAS No.:22736-85-2
Molecular Formula:C14H11 F2 N O3 S
Molecular Weight:311.309
Hs Code.:2935009090
UNII:E96467495S
DSSTox Substance ID:DTXSID90177275
Nikkaji Number:J11.481B
Wikidata:Q27277039
NCI Thesaurus Code:C65384
ChEMBL ID:CHEMBL2110671
Mol file:22736-85-2.mol

Synonyms:3-benzoyldifluoromethanesulfonanilide sodium;diflumidone;diflumidone sodium;diflumidone sodium salt;MBR 4164-8;R-807

Suppliers and Price of Diflumidone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIFLUMIDONE 95.00%
5MG
$ 503.05

Total 6 raw suppliers

Chemical Property of Diflumidone

Chemical Property:

Vapor Pressure:6.7E-08mmHg at 25°C
Boiling Point:438.8°Cat760mmHg
PKA:5.26±0.50(Predicted)
Flash Point:219.2°C
PSA：71.62000
Density:1.419g/cm³
LogP:4.03570
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:311.04277071
Heavy Atom Count:21
Complexity:455

Purity/Quality:

99% ^*data from raw suppliers

DIFLUMIDONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=CC(=CC=C2)NS(=O)(=O)C(F)F
Uses Diflumidone, is a novel non-steroidal antiinflammatory drug.

Technology Process of Diflumidone

There total 3 articles about Diflumidone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₈H₂₀F₂NO₆PS

: 22736-85-2
N-(3-benzoylphenyl)-1,1-difluoromethanesulfonamide

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 25 ℃; for 15h;
DOI:10.1002/anie.201607231

Reference yield:

: N-[(diethylphosphonodifluoromethyl)sulfanyl]-3-benzoylaniline

: 22736-85-2
N-(3-benzoylphenyl)-1,1-difluoromethanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 h / 0 - 20 °C

2: sodium hydroxide / tetrahydrofuran; water / 15 h / 25 °C

With 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/anie.201607231