alpha-((4-Methyl-1-piperazinyl)methyl)-2-quinolinemethanol

Base Information

Chemical Name:alpha-((4-Methyl-1-piperazinyl)methyl)-2-quinolinemethanol
CAS No.:126921-33-3
Molecular Formula:C₁₆H₂₁N₃O
Molecular Weight:271.362
Hs Code.:
DSSTox Substance ID:DTXSID30925737

Synonyms:BRN 4454793;alpha-((4-Methyl-1-piperazinyl)methyl)-2-quinolinemethanol;126921-33-3;2-Quinolinemethanol, alpha-((4-methyl-1-piperazinyl)methyl)-;DTXSID30925737;LS-142018;2-(4-Methylpiperazin-1-yl)-1-(quinolin-2-yl)ethan-1-ol

Suppliers and Price of alpha-((4-Methyl-1-piperazinyl)methyl)-2-quinolinemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of alpha-((4-Methyl-1-piperazinyl)methyl)-2-quinolinemethanol

Chemical Property:

Vapor Pressure:1.81E-08mmHg at 25°C
Boiling Point:438.6°Cat760mmHg
Flash Point:219.1°C
Density:1.167g/cm³
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:271.168462302
Heavy Atom Count:20
Complexity:304

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)CC(C2=NC3=CC=CC=C3C=C2)O

Technology Process of alpha-((4-Methyl-1-piperazinyl)methyl)-2-quinolinemethanol

There total 5 articles about alpha-((4-Methyl-1-piperazinyl)methyl)-2-quinolinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4-Methyl-piperazin-1-yl)-1-quinolin-2-yl-ethanone

: 126921-33-3
2-(4-Methyl-piperazin-1-yl)-1-quinolin-2-yl-ethanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 4h; Heating;

Reference yield:

: 50342-01-3
quinolin-2-ylcarbonyl chloride

: 126921-33-3
2-(4-Methyl-piperazin-1-yl)-1-quinolin-2-yl-ethanol

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / diethyl ether / 12 h / 0 °C

2: 80 percent / 48percent hydrobromic acid / diethyl ether / 0.5 h / 0 °C

3: benzene / 0 - 5 °C

4: LiAlH₄ / tetrahydrofuran; diethyl ether / 4 h / Heating

With lithium aluminium tetrahydride; hydrogen bromide; In tetrahydrofuran; diethyl ether; benzene;

Reference yield:

: 93-10-7,1199266-78-8
quinoline-2-carboxylic acid

: 126921-33-3
2-(4-Methyl-piperazin-1-yl)-1-quinolin-2-yl-ethanol

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / SOCl₂

2: 100 percent / diethyl ether / 12 h / 0 °C

3: 80 percent / 48percent hydrobromic acid / diethyl ether / 0.5 h / 0 °C

4: benzene / 0 - 5 °C

5: LiAlH₄ / tetrahydrofuran; diethyl ether / 4 h / Heating

With lithium aluminium tetrahydride; thionyl chloride; hydrogen bromide; In tetrahydrofuran; diethyl ether; benzene;