Technology Process of 2-Cyclohexen-1-one,
3,5-dimethyl-4-[[1-(trimethylsilyl)cyclopropyl]methylene]-
There total 6 articles about 2-Cyclohexen-1-one,
3,5-dimethyl-4-[[1-(trimethylsilyl)cyclopropyl]methylene]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 99 percent / ethylzinc iodide / diethyl ether / 15 h / Ambient temperature
2: 80 percent / MnO2 / CH2Cl2 / 48 h / Ambient temperature
3: 90 percent / pyridinium tosylate / methanol; benzene / 15 h / Ambient temperature
4: 70 percent / TiCl4 / CH2Cl2 / 4 h / -78 °C
5: 81 percent / anhydrous sodium acetate / acetic acid / 10 h / Heating
6: 2) H3O+
With
manganese(IV) oxide; oxonium; sodium acetate; pyridinium p-toluenesulfonate; titanium tetrachloride; ethylzinc iodide;
In
methanol; diethyl ether; dichloromethane; acetic acid; benzene;
DOI:10.1021/jo00193a030
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 80 percent / MnO2 / CH2Cl2 / 48 h / Ambient temperature
2: 90 percent / pyridinium tosylate / methanol; benzene / 15 h / Ambient temperature
3: 70 percent / TiCl4 / CH2Cl2 / 4 h / -78 °C
4: 81 percent / anhydrous sodium acetate / acetic acid / 10 h / Heating
5: 2) H3O+
With
manganese(IV) oxide; oxonium; sodium acetate; pyridinium p-toluenesulfonate; titanium tetrachloride;
In
methanol; dichloromethane; acetic acid; benzene;
DOI:10.1021/jo00193a030
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 70 percent / TiCl4 / CH2Cl2 / 4 h / -78 °C
2: 81 percent / anhydrous sodium acetate / acetic acid / 10 h / Heating
3: 2) H3O+
With
oxonium; sodium acetate; titanium tetrachloride;
In
dichloromethane; acetic acid;
DOI:10.1021/jo00193a030
