5-Chloro-1-methyl-4-nitroimidazole

Base Information

Chemical Name:5-Chloro-1-methyl-4-nitroimidazole
CAS No.:4897-25-0
Molecular Formula:C4H4ClN3O2
Molecular Weight:161.548
Hs Code.:2933290090
European Community (EC) Number:225-521-2
NSC Number:7852
UNII:P917JW98BD
DSSTox Substance ID:DTXSID00197646
Nikkaji Number:J2.221G
Wikidata:Q27286392
ChEMBL ID:CHEMBL1610328
Mol file:4897-25-0.mol

Synonyms:1-methyl- 4-nitro-5-chloroimidazoles;1-methyl-5-chloro-4-nitroimidazole;5-chloro-1-methyl-4-nitroimidazole;CMNI;NSC 7852

Suppliers and Price of 5-Chloro-1-methyl-4-nitroimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Chloro-1-methyl-4-nitroimidazole
5g
$ 120.00

TCI Chemical
5-Chloro-1-methyl-4-nitroimidazole >98.0%(N)
5g
$ 99.00

SynQuest Laboratories
5-Chloro-1-methyl-4-nitro-1H-imidazole
100 g
$ 154.00

SynQuest Laboratories
5-Chloro-1-methyl-4-nitro-1H-imidazole
5 g
$ 23.00

SynQuest Laboratories
5-Chloro-1-methyl-4-nitro-1H-imidazole
25 g
$ 55.00

Sigma-Aldrich
5-Chloro-1-methyl-4-nitroimidazole 98%
5g
$ 119.00

Frontier Specialty Chemicals
5-Chloro-1-methyl-4-nitroimidazole 98%
25g
$ 505.00

Frontier Specialty Chemicals
5-Chloro-1-methyl-4-nitroimidazole 98%
5g
$ 127.00

Crysdot
5-Chloro-1-methyl-4-nitroimidazole 95%
100g
$ 70.00

ChemScene
5-Chloro-1-methyl-4-nitroimidazole
500g
$ 190.00

Total 126 raw suppliers

Chemical Property of 5-Chloro-1-methyl-4-nitroimidazole

Chemical Property:

Appearance/Colour:White solid
Vapor Pressure:4.08E-05mmHg at 25°C
Melting Point:148-150 °C(lit.)
Refractive Index:1.648
Boiling Point:362.3 °C at 760 mmHg
PKA:-1.37±0.61(Predicted)
Flash Point:172.9 °C
PSA：63.64000
Density:1.65 g/cm³
LogP:1.50490
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:160.9992041
Heavy Atom Count:10
Complexity:148

Purity/Quality:

99% ^*data from raw suppliers

5-Chloro-1-methyl-4-nitroimidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=NC(=C1Cl)[N+](=O)[O-]
Description 5-Chloro-1-methyl-4-nitroimidazole is an imidazole derivative. It is useful in the rapid mix experiments to investigate the mechanism of anomalous radiosensitization of mammalian cells. It can also be used in the synthesis of 5-aryl-1-methyl-4-nitroimidazoles, via Suzuki coupling with arylboronic acids, catalyzed by dichlorobis-(triphenylphosphine) palladium (II), K2CO3 and tetrabutylammonium bromide. 5-Chloro-1-methyl-4-nitroimidazole is an intermediate in azathioprine synthesis, also present in the end product. It induced contact dermatitis in a man working on azathioprine synthesis. Cross reactivity is possible with imidazoles tioconazole, and econazole.
Uses 5-Chloro-1-methyl-4-nitroimidazole (CMNI) is suitable for use in the rapid mix experiments to investigate the mechanism of anomalous radiosensitization of mammalian cells by CMNI. It may be used in the synthesis of 5-aryl-1-methyl-4-nitroimidazoles, via Suzuki coupling with arylboronic acids, catalyzed by dichlorobis-(triphenylphosphine)palladium(II), K2CO3 and tetrabutylammonium bromide.

Technology Process of 5-Chloro-1-methyl-4-nitroimidazole

There total 8 articles about 5-Chloro-1-methyl-4-nitroimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%