Micafungin sodium

Base Information

• Chemical Name: Micafungin sodium
• CAS No.: 208538-73-2
• Molecular Formula: C56H70N9NaO23S
• Molecular Weight: 1292.26
• Mol file: 208538-73-2.mol

Synonyms:Funguard (TN);FK463;Mycamine (TN);FK 463;Micafungin sodium (JAN);Pneumocandin A0,1-[(4R,5R)-4,5-dihydroxy- N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]- benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4- [4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-,monosodium salt;Pneumocandin A0, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(5-(5-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxy-3-(sulfooxy)phenyl)-L-threonine)-, monosodium salt;Funguard;Mycamine;

Chemical Property of Micafungin sodium

Chemical Property:

• Appearance/Colour: Off-White Solid
• PSA: 521.35000
• LogP: -0.88160
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)

Purity/Quality:

99% ^*data from raw suppliers

Micafungin sodium ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: The semi-synthetic echinocandin antifungal agent, micafungin sodium (15), is a 1,3-β-glucan synthase inhibitor discovered by Fujisawa. It is for the treatment and prevention of infections caused by Aspergillus and Candida such as fungemia, respiratory mycosis and gastrointestinal mycosis.
• Uses: An echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Micafungin sodium is the salt of the semi-synthetic cyclic lipopeptide, micafungin, a member of the echinocandin class that was reported in 1999 from Fujisawa in Japan. The sodium salt takes advantage of the aryl sulphate moiety providing improved water solubility and is the preferred salt for pharmaceutical applications. Like all echinocandins, micafungin inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Micafungin is an echinocandin antifungal that inhibits 1,3-β-D-glucan synthesis. It has fungicidal activity against virtually all species of Candida, including those resistant to fluconazole, and is fungistatic against Aspergillus spp.[Cayman Chemical]