1,2,3,4,4a,9,9a,10-Octahydroacridine

Base Information

• Chemical Name: 1,2,3,4,4a,9,9a,10-Octahydroacridine
• CAS No.: 92039-20-8
• Molecular Formula: C13H17N
• Molecular Weight: 187.285
• DSSTox Substance ID: DTXSID40491352
• Nikkaji Number: J259.111A
• Mol file: 92039-20-8.mol

Synonyms:1,2,3,4,4a,9,9a,10-octahydroacridine;92039-20-8;SCHEMBL5208279;DTXSID40491352;AKOS023412118;EN300-159920;Z1262562740

Chemical Property of 1,2,3,4,4a,9,9a,10-Octahydroacridine

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 187.136099547
• Heavy Atom Count: 14
• Complexity: 201

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2C(C1)CC3=CC=CC=C3N2

Technology Process of 1,2,3,4,4a,9,9a,10-Octahydroacridine

There total 18 articles about 1,2,3,4,4a,9,9a,10-Octahydroacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

acridine (260-94-6) → 1,2,3,4-tetrahydroacridine (3295-64-5) + acridine (92-81-9) + 1,2,3,4,5,6,7,8-octahydroacridine (1658-08-8) + 5,6,7,8,8a,9,10,10a-octahydroacridine (92039-20-8)

Guidance literature:

With hydrogen; palladium/alumina; In ethanol; at 100 ℃; for 15h; under 53200 Torr; Further byproducts given; other catalysts;

Reference yield: 85.0%

acridine (260-94-6) → tetradecahydroacridine (20178-49-8,114580-62-0,802034-48-6,802316-12-7) + 1,2,3,4-tetrahydroacridine (3295-64-5) + acridine (92-81-9) + 1,2,3,4,5,6,7,8-octahydroacridine (1658-08-8) + 5,6,7,8,8a,9,10,10a-octahydroacridine (92039-20-8)

Guidance literature:

With hydrogen; palladium/alumina; In ethanol; at 100 ℃; for 0.25h; under 53200 Torr; Product distribution; other catalysts;

Reference yield: 80.0%

acridine (92-81-9) → 1,2,3,4-tetrahydroacridine (3295-64-5) + (4aα,8aα,9aα,10aβ)-Tetradecahydroacridine (16726-19-5,20178-49-8,24526-17-8,26432-22-4,114580-62-0) + (+/-)-(4aSR,9aRS)-1,2,3,4,4a,9,9a,10-octahydroacridine (20378-05-6,20378-06-7,92039-20-8) + (+/-)-(4aRS,9aRS)-1,2,3,4,4a,9a,10-octahydroacridine (20378-05-6,20378-06-7,92039-20-8)

Guidance literature:

With hydrogen; palladium/alumina; In decalin; at 150 ℃; for 0.166667h; under 53200 Torr; Further byproducts given;

upstream raw materials:

acridine

acridine

1,2,3,4-tetrahydroacridine

1,4-dioxane

Downstream raw materials:

1,2,3,4-tetrahydroacridine

(4aS,9aS)-1,2,3,4,4a,9,9a,10-octahydroacridine

(4aR,9aR)-1,2,3,4,4a,9,9a,10-octahydroacridine

1,2,3,4,5,6,7,8-octahydroacridine