Technology Process of 3,3',5-Triiodothyronamine
There total 13 articles about 3,3',5-Triiodothyronamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate; DL-dithiothreitol; Naphthalene-1,8-diselenol;
In
aq. phosphate buffer; acetonitrile;
at 37 ℃;
pH=7;
regioselective reaction;
DOI:10.1039/c6ob01375a
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium hydrogencarbonate / tetrahydrofuran; water / 24 h
2: Iodine monochloride; sodium methylate / N,N-dimethyl-formamide; dichloromethane / 3 h / -40 °C
3: copper diacetate; triethylamine; pyridine / dichloromethane / 12 h / Molecular sieve
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
5: Iodine monochloride; N-butylamine / N,N-dimethyl-formamide; dichloromethane / 0.5 h / 0 °C
6: dichloromethane / 1 h / 20 °C
7: Naphthalene-1,8-diselenol; DL-dithiothreitol; sodium tetrahydroborate / aq. phosphate buffer; acetonitrile / 37 °C / pH 7
With
pyridine; sodium tetrahydroborate; DL-dithiothreitol; tetrabutyl ammonium fluoride; sodium methylate; copper diacetate; Iodine monochloride; sodium hydrogencarbonate; N-butylamine; triethylamine; Naphthalene-1,8-diselenol;
In
tetrahydrofuran; aq. phosphate buffer; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1039/c6ob01375a