Technology Process of 4-Piperidinecarbonyl chloride, 1-benzoyl-3-ethenyl-, cis-
There total 6 articles about 4-Piperidinecarbonyl chloride, 1-benzoyl-3-ethenyl-, cis- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 67 percent / NaH / dimethylformamide / 5.5 h / 0 °C
2: 92 percent / pyridinium p-toluenesulfonate / methanol / 4 h / Heating
3: 73 percent / NEt3, 2-chloro-1-methylpyridinium iodide / acetonitrile / Heating
4: 93 percent / LDA
5: 92 percent / HF / acetonitrile
6: 1.) NaH; 2.) oxalyl chloride / 1.) benzene; 2.) room temp. 30 min
With
oxalyl dichloride; hydrogen fluoride; 2-chloro-1-methyl-pyridinium iodide; pyridinium p-toluenesulfonate; sodium hydride; triethylamine; lithium diisopropyl amide;
In
methanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0040-4020(01)90572-1
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 92 percent / pyridinium p-toluenesulfonate / methanol / 4 h / Heating
2: 73 percent / NEt3, 2-chloro-1-methylpyridinium iodide / acetonitrile / Heating
3: 93 percent / LDA
4: 92 percent / HF / acetonitrile
5: 1.) NaH; 2.) oxalyl chloride / 1.) benzene; 2.) room temp. 30 min
With
oxalyl dichloride; hydrogen fluoride; 2-chloro-1-methyl-pyridinium iodide; pyridinium p-toluenesulfonate; sodium hydride; triethylamine; lithium diisopropyl amide;
In
methanol; acetonitrile;
DOI:10.1016/S0040-4020(01)90572-1
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 92 percent / HF / acetonitrile
2: 1.) NaH; 2.) oxalyl chloride / 1.) benzene; 2.) room temp. 30 min
With
oxalyl dichloride; hydrogen fluoride; sodium hydride;
In
acetonitrile;
DOI:10.1016/S0040-4020(01)90572-1
