4-(4-Chlorophenyl)-3-(4-fluorophenyl)butan-2-one

Base Information

Chemical Name:4-(4-Chlorophenyl)-3-(4-fluorophenyl)butan-2-one
CAS No.:922501-76-6
Molecular Formula:C16H14ClFO
Molecular Weight:276.738
Hs Code.:
DSSTox Substance ID:DTXSID70582646

Synonyms:4-(4-Chlorophenyl)-3-(4-fluorophenyl)butan-2-one;922501-76-6;DTXSID70582646

Suppliers and Price of 4-(4-Chlorophenyl)-3-(4-fluorophenyl)butan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-(4-Chlorophenyl)-3-(4-fluorophenyl)butan-2-one

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:276.0717209
Heavy Atom Count:19
Complexity:291

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C(CC1=CC=C(C=C1)Cl)C2=CC=C(C=C2)F

Technology Process of 4-(4-Chlorophenyl)-3-(4-fluorophenyl)butan-2-one

There total 4 articles about 4-(4-Chlorophenyl)-3-(4-fluorophenyl)butan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34837-84-8
4-fluorobenzeneacetic acid methyl ester

: 922501-76-6
4-(4-chloro-phenyl)-3-(4-fluoro-phenyl)-butan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hexamethyldisilazide / -78 - 20 °C

2: Me₂AlCl / 20 °C

3: 0 °C

With sodium hexamethyldisilazane; dimethylaluminum chloride;
DOI:10.1021/jm060996+

Reference yield:

: 922501-65-3
3-(4-chloro-phenyl)-2-(4-fluoro-phenyl)-propionic acid methyl ester

: 922501-76-6
4-(4-chloro-phenyl)-3-(4-fluoro-phenyl)-butan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: Me₂AlCl / 20 °C

2: 0 °C

With dimethylaluminum chloride;
DOI:10.1021/jm060996+

Reference yield:

: 622-95-7
4-chlorobenzyl bromide

: 922501-76-6
4-(4-chloro-phenyl)-3-(4-fluoro-phenyl)-butan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hexamethyldisilazide / -78 - 20 °C

2: Me₂AlCl / 20 °C

3: 0 °C

With sodium hexamethyldisilazane; dimethylaluminum chloride;
DOI:10.1021/jm060996+