CID 5232348

Base Information

• Chemical Name: CID 5232348
• CAS No.: 2937-53-3
• Molecular Formula: C2H7 N O3 S2
• Molecular Weight: 157.214
• Hs Code.: 29309099
• Mol file: 2937-53-3.mol

Synonyms:

Chemical Property of CID 5232348

Chemical Property:

• Melting Point: 191-194 °C
• Refractive Index: 1.5130 (estimate)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 114.07000
• Density: 1.608g/cm³
• LogP: 1.26220
• XLogP3: -3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 156.98673543
• Heavy Atom Count: 8
• Complexity: 121

Purity/Quality:

99.5% ^*data from raw suppliers

1-azaniumyl-2-sulfonatosulfanylethane ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CSS(=O)(=O)[O-])[NH3+]

Technology Process of CID 5232348

There total 6 articles about CID 5232348 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.1%

2-chloroethanamine hydrochloride (870-24-6) → 2-aminoethylthiosulfonic acid (2937-53-3)

Guidance literature:

With sodium thiosulfate; In water; for 0.5h; Heating;

DOI:10.1007/BF00766260

Reference yield:

Cysteamine (60-23-1) → 2-aminoethylthiosulfonic acid (2937-53-3)

Guidance literature:

With pyridine-SO₃ complex; In N,N-dimethyl-formamide;

DOI:10.1021/jo00945a016

Reference yield:

2-Chloro-ethylamine; hydrobromide → 2-aminoethylthiosulfonic acid (2937-53-3)

Guidance literature:

With sodium thiosulfate; In water;

DOI:10.1016/S0040-4020(01)98555-2

upstream raw materials:

2-chloroethanamine hydrochloride

2-bromoethylamine hydrobromide

ethyleneimine

Cysteamine

Downstream raw materials:

2,2'-dithio-bis[ethylamine]

bis-[2-(3-phenylureido)ethyl]disulfide

N,N'-(2,2'-disulfanediylbis(ethane-2,1-diyl))dibenzamide

2-n-Undecylamino-ethanthioschwefelsaeure

Refernces

10.1021/jm00279a022

The research investigates the antiradiation activity of various derivatives of substituted 2-aminoethanethiols, focusing on the effects of different sulfur-covering groups such as Bunte salts, thiols, disulfides, and thiazolidines. The purpose was to identify effective radioprotective agents, with the study finding that Bunte salts generally exhibited the best activity, followed by thiols and disulfides, while thiazolidines were the least effective. S-2-aminoethyl hydrogen thiosulfate (I) is a key compound that serves as the core structure for developing antiradiation agents. It is an N-substituted derivative where the nitrogen is modified with various substituents to enhance its radioprotective properties. The study explores different modifications of this compound by incorporating various sulfur-covering groups such as thiols, disulfides, and thiazolidines to assess their impact on antiradiation activity. The effectiveness of these derivatives is highly sensitive to minor structural modifications of the nitrogen substituent, and the study aims to determine how changes in the sulfur-covering function affect the radioprotective properties. S-2-aminoethyl hydrogen thiosulfate and its derivatives are crucial in this investigation as they form the basis for comparing the antiradiation activity among different sulfur-covering groups.