Zymostenol

Base Information

• Chemical Name: Zymostenol
• CAS No.: 566-97-2
• Molecular Formula: C27H46 O
• Molecular Weight: 386.65
• UNII: L3GY707BLC
• DSSTox Substance ID: DTXSID30205162
• Nikkaji Number: J488.411F
• Wikidata: Q27101995
• Metabolomics Workbench ID: 34402
• Mol file: 566-97-2.mol

Synonyms:5alpha-cholest-8(9)-en-3beta-ol;8(9)-cholestenol;delta(8)-cholestenol;zymostenol;zymostenol, (3beta)-isomer

Chemical Property of Zymostenol

Chemical Property:

• Boiling Point: 480.1°Cat760mmHg
• Flash Point: 209.1°C
• PSA: 20.23000
• Density: 0.98g/cm³
• LogP: 7.53280
• Storage Temp.: -20°C
• XLogP3: 8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 386.354866087
• Heavy Atom Count: 28
• Complexity: 603

Purity/Quality:

98%,99%, ^*data from raw suppliers

Zymostenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3=C2CCC4C3(CCC(C4)O)C)C
• Isomeric SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C
• Uses: Zymostenol, is the derivative of Zymosterol (Z701520), which is an sterol intermediate in the biosynthesis of cholesterol (C432501). Zymostenol has been used to study its accumulation and its inhibitory actions on Δ8,7-sterol isomerase (EBP).

Technology Process of Zymostenol

There total 26 articles about Zymostenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cholesta-5,8(9)-dien-3β-ol (70741-38-7) → 5α-cholest-8-en-3β-ol (566-97-2)

Guidance literature:

With hydrogen; nickel; In ethanol; Yield given;

DOI:10.1021/jo00330a006

Reference yield:

7-Dehydrocholesteryl acetate (1059-86-5) → 5α-cholest-8-en-3β-ol (566-97-2)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene / 4 h / Heating

2: Li / various solvent(s) / -20 °C / 30 min longer than required for the initial apperance of a blue color

3: H₂ / Raney nickel / ethanol

With hydrogen; lithium; nickel; In ethanol; benzene;

DOI:10.1021/jo00330a006

Reference yield:

7α-cholesta-5,8-dien-3β-yl acetate (3914-89-4) → 5α-cholest-8-en-3β-ol (566-97-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Li / various solvent(s) / -20 °C / 30 min longer than required for the initial apperance of a blue color

2: H₂ / Raney nickel / ethanol

With hydrogen; lithium; nickel; In ethanol;

DOI:10.1021/jo00330a006

upstream raw materials:

5α-cholesta-6,8-dien-3β-ol

5α-cholest-8-en-3-one

aluminum isopropoxide

isopropyl alcohol

Downstream raw materials:

5α-cholesten-(8)-yl-(3α)-acetate

5α-cholest-8(14)-en-3β-ol

Refernces

• 1、 Anastasia,Fiecchi,Galli. "Synthesis of cholesta-5,8-dien-3β-ol". . p. 3421 - 3422. Retrieved 1981.