(2-Hydroxyphenyl)(phenyl)acetic acid

Base Information

• Chemical Name: (2-Hydroxyphenyl)(phenyl)acetic acid
• CAS No.: 25173-82-4
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.247
• NSC Number: 27569
• DSSTox Substance ID: DTXSID10282714
• Mol file: 25173-82-4.mol

Synonyms:25173-82-4;(2-hydroxyphenyl)(phenyl)acetic acid;NSC27569;2-Oxy-diphenylessig;SCHEMBL11363822;DTXSID10282714;NSC-27569

Chemical Property of (2-Hydroxyphenyl)(phenyl)acetic acid

Chemical Property:

• Vapor Pressure: 4.39E-07mmHg at 25°C
• Boiling Point: 399°Cat760mmHg
• Flash Point: 209.3°C
• Density: 1.274g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 228.078644241
• Heavy Atom Count: 17
• Complexity: 258

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2O)C(=O)O

Technology Process of (2-Hydroxyphenyl)(phenyl)acetic acid

There total 11 articles about (2-Hydroxyphenyl)(phenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-phenyl-1-(2-hydroxyphenyl)ethene (39477-86-6) + (2-hydroxy-phenyl)-phenyl-acetic acid (25173-82-4)

Guidance literature:

With potassium hydroxide; at 200 ℃; unter Druck;

Reference yield:

2-(1-phenylpropyl)phenol (61986-73-0) → (2-hydroxy-phenyl)-phenyl-acetic acid (25173-82-4)

Guidance literature:

With permanganate(VII) ion;

Reference yield:

3,4-dihydro-4-phenyl-2H-chromene (21763-04-2) → (2-hydroxy-phenyl)-phenyl-acetic acid (25173-82-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium; alcohol

2: permanganate; alkali

With ethanol; sodium; permanganate(VII) ion;

upstream raw materials:

2-(1-phenylpropyl)phenol

3-phenyl-3H-benzofuran-2-one

3-phenyl-2,3-dihydrobenzofuran

3,4-dihydro-4-phenyl-2H-chromene

Downstream raw materials:

3-phenyl-3H-benzofuran-2-one

(2-benzoyloxy-phenyl)-phenyl-acetic acid