Methenolone acetate

Base Information

• Chemical Name: Methenolone acetate
• CAS No.: 434-05-9
• Molecular Formula: C22H32O3
• Molecular Weight: 344.494
• Hs Code.: 2942000000
• European Community (EC) Number: 207-097-0
• NSC Number: 74226
• UNII: W75590VPKQ
• DSSTox Substance ID: DTXSID40963004
• Nikkaji Number: J5.730D
• Wikipedia: Metenolone_acetate
• Wikidata: Q27292427
• NCI Thesaurus Code: C170169
• ChEMBL ID: CHEMBL2106880
• Mol file: 434-05-9.mol

Synonyms:metenolone acetate;methenolone acetate;methenolone acetate, (17beta)-isomer;Primobolan;Primobolan S

Chemical Property of Methenolone acetate

Chemical Property:

• Vapor Pressure: 5.54E-08mmHg at 25°C
• Melting Point: 138-139°
• Refractive Index: 1.536
• Boiling Point: 441.2 °C at 760 mmHg
• Flash Point: 189.9 °C
• PSA: 43.37000
• Density: 1.1 g/cm³
• LogP: 4.69600
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 344.23514488
• Heavy Atom Count: 25
• Complexity: 635

Purity/Quality:

99.0% Min., ^*data from raw suppliers

Methenolone acetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=O)CC2C1(C3CCC4(C(C3CC2)CCC4OC(=O)C)C)C
• Isomeric SMILES: CC1=CC(=O)C[C@H]2[C@]1([C@H]3CC[C@]4([C@H]([C@@H]3CC2)CC[C@@H]4OC(=O)C)C)C
• Description: Methenolone acetate (Brand name: Primobolan) is a synthetic, orally active anabolic-androgenic steroid and dihydrotestosterone (DHT) derivative. It can be used for the treatment of bone marrow disease and anemia. Methenolone acetate is known for its higher therapeutic efficiency and lower hepatic toxicity compared with its 17 alpha- alkylated analogs. However, it is frequently abused in human sports because of its capability of increasing muscle strength as well as promoting performance and aggressiveness. It is capable of enhancing performance in racehorses.
• Uses: Methenolone acetate is an anabolic steroid. This is a controlled substance.

Technology Process of Methenolone acetate

There total 4 articles about Methenolone acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

17β-acetoxy-1-methyl-androsta-1,4-dien-3-one (1099-80-5) → 3-oxo-1-methyl-5α-androst-1-en-17β-yl acetate (434-05-9)

Guidance literature:

With thallium(III) nitrate trihydrate; In diethylene glycol dimethyl ether; for 24h; Ambient temperature;

Reference yield:

→ 17β-Hydroxy-1-methyl-Δ1-5α-androstenon-(3)-acetat (434-05-9,49566-70-3,79732-38-0)

Guidance literature:

<Δ^2'-Pyrazolino-4'.3':1.2-androstanol-(17β)-on-(3)>, 1.)saures Al2O3 / CCl4, 2.)Acetnhydrid / Pyridin;

Reference yield:

→ 1-Methyl-androst-1-en-17β-ol-3-on-17-acetat (434-05-9,49566-70-3,79732-38-0)

Guidance literature:

(Δ^2'-Pyrazolino)-4',3':1,2-androstan-17β-ol-3-on, 1.) Δ in Chinolin, 2.) Ac2O/Pyridin;

upstream raw materials:

17β-acetoxy-1-methyl-androsta-1,4-dien-3-one

Downstream raw materials:

17β-acetyloxy-1-methyl-2-<(phenylthio)methyl>-5α-androst-1-en-3-one

Refernces