{1-[(3-Chlorophenyl)methyl]-1H-indol-3-yl}methanol

Base Information

Chemical Name:{1-[(3-Chlorophenyl)methyl]-1H-indol-3-yl}methanol
CAS No.:92407-90-4
Molecular Formula:C16H14ClNO
Molecular Weight:271.746
Hs Code.:
ChEMBL ID:CHEMBL1775135
DSSTox Substance ID:DTXSID90534900
Nikkaji Number:J3.353.321G
NSC Number:743380
Wikidata:Q82408950

Synonyms:1-((3-chlorophenyl)methyl)-1H-indole-3-carbinol;NSC-743380

Suppliers and Price of {1-[(3-Chlorophenyl)methyl]-1H-indol-3-yl}methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of {1-[(3-Chlorophenyl)methyl]-1H-indol-3-yl}methanol

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:271.0763918
Heavy Atom Count:19
Complexity:299

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CN2CC3=CC(=CC=C3)Cl)CO

Technology Process of {1-[(3-Chlorophenyl)methyl]-1H-indol-3-yl}methanol

There total 4 articles about {1-[(3-Chlorophenyl)methyl]-1H-indol-3-yl}methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 90815-01-3
1?(3?chlorobenzyl)?1H?indole?3?carbaldehyde

: 92407-90-4
1-[(3-chlorophenyl)methyl]-1H-indole-3-methanol

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol; Ambient temperature;
DOI:10.1002/ardp.19843170803

Reference yield:

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 92407-90-4
1-[(3-chlorophenyl)methyl]-1H-indole-3-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / 1.) NaH / 1.) DMF, 2.) DMF, room temp., 15 h

2: 86 percent / NaBH₄ / propan-2-ol / Ambient temperature

With sodium tetrahydroborate; sodium hydride; In isopropyl alcohol;
DOI:10.1002/ardp.19843170803

Reference yield:

: 620-20-2,130468-19-8
1-Chloro-3-chloromethyl-benzene

: 92407-90-4
1-[(3-chlorophenyl)methyl]-1H-indole-3-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / 1.) NaH / 1.) DMF, 2.) DMF, room temp., 15 h

2: 86 percent / NaBH₄ / propan-2-ol / Ambient temperature

With sodium tetrahydroborate; sodium hydride; In isopropyl alcohol;
DOI:10.1002/ardp.19843170803