1,2,5-Oxadiazole, 3-bromo-4-phenyl-, 2-oxide

Base Information

• Chemical Name: 1,2,5-Oxadiazole, 3-bromo-4-phenyl-, 2-oxide
• CAS No.: 92408-31-6
• Molecular Formula: C8H5BrN2O2
• Molecular Weight: 241.044
• Mol file: 92408-31-6.mol

Synonyms:

Chemical Property of 1,2,5-Oxadiazole, 3-bromo-4-phenyl-, 2-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,5-Oxadiazole, 3-bromo-4-phenyl-, 2-oxide

There total 1 articles about 1,2,5-Oxadiazole, 3-bromo-4-phenyl-, 2-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

1-Bromo-2-phenylacetylene (932-87-6) → 3-Bromo-4-phenylfuroxan (92408-31-6)

Guidance literature:

With nitrous anhydride; In Petroleum ether; for 6h; Ambient temperature;

DOI:10.1002/ardp.19843170809

Reference yield:

3-Bromo-4-phenylfuroxan (92408-31-6) → 3-Bromo-4-phenylfurazan (92408-33-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 4 h / 110 °C

2: 60 percent / SnCl₂*2H₂O, conc. aq. HCl / acetic acid / 48 h / 95 °C

With hydrogenchloride; tin(ll) chloride; In acetic acid;

DOI:10.1002/ardp.19843170809

Reference yield:

3-Bromo-4-phenylfuroxan (92408-31-6) → 4-Bromo-3-phenylfuroxan (92408-32-7)

Guidance literature:

at 110 ℃; for 4h;

DOI:10.1002/ardp.19843170809

upstream raw materials:

1-Bromo-2-phenylacetylene

Downstream raw materials:

4-Bromo-3-phenylfuroxan

3-Bromo-4-phenylfurazan