tert-butyl 1-[(2R,3S)-2-hydroxy-3-{[N~2~-(naphthalen-2-ylcarbonyl)-L-asparaginyl]amino}-4-phenylbutyl]-L-prolinate

Base Information

• Chemical Name: tert-butyl 1-[(2R,3S)-2-hydroxy-3-{[N~2~-(naphthalen-2-ylcarbonyl)-L-asparaginyl]amino}-4-phenylbutyl]-L-prolinate
• CAS No.: 127749-96-6
• Molecular Formula: C34H42 N4 O6
• Molecular Weight: 602.7205
• Mol file: 127749-96-6.mol

Synonyms:L-Proline,1-[3-[[4-amino-2-[(2-naphthalenylcarbonyl)amino]-1,4-dioxobutyl]amino]-2-hydroxy-4-phenylbutyl]-,1,1-dimethylethyl ester, [2R-[2R*,3S*(S*)]]-

Chemical Property of tert-butyl 1-[(2R,3S)-2-hydroxy-3-{[N~2~-(naphthalen-2-ylcarbonyl)-L-asparaginyl]amino}-4-phenylbutyl]-L-prolinate

Chemical Property:

• Vapor Pressure: 1.68E-35mmHg at 25°C
• Boiling Point: 907.3°Cat760mmHg
• Flash Point: 502.5°C
• Density: 1.233g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-butyl 1-[(2R,3S)-2-hydroxy-3-{[N~2~-(naphthalen-2-ylcarbonyl)-L-asparaginyl]amino}-4-phenylbutyl]-L-prolinate

There total 1 articles about tert-butyl 1-[(2R,3S)-2-hydroxy-3-{[N~2~-(naphthalen-2-ylcarbonyl)-L-asparaginyl]amino}-4-phenylbutyl]-L-prolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[3(S)-[[L-asparaginyl]amino]-2(R)-hydroxy-4-phenylbutyl]-L-proline tert.butyl ester + 2-naphthaloyl chloride (2243-83-6) → N-[2(R)-hydroxy-3(S)-[[N-(2-naphthoyl)-L-asparaginyl]amino]-4-phenylbutyl]-L-proline tert.butyl ester (127749-96-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane;

upstream raw materials:

2-naphthaloyl chloride