l-Alminoprofen

Base Information

• Chemical Name: l-Alminoprofen
• CAS No.: 54362-71-9
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219.283
• Mol file: 54362-71-9.mol

Synonyms:Benzeneaceticacid, a-methyl-4-[(2-methyl-2-propenyl)amino]-,(-)- (9CI); (-)-Alminoprofen; l-Alminoprofen

Chemical Property of l-Alminoprofen

Chemical Property:

• PSA: 49.33000
• LogP: 2.93570

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of l-Alminoprofen

There total 2 articles about l-Alminoprofen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ alminoprofen (39718-89-3,54362-71-9,71589-39-4)

Guidance literature:

Amin durch Alkyl.;

Reference yield:

2-(4-cyano-phenyl)-propionic acid (362052-00-4) → alminoprofen (39718-89-3,54362-71-9,71589-39-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: diazomethyl-trimethyl-silane / toluene / 2 h / 20 °C

2.1: hydroxylamine / water monomer; ethanol / 3 h / Reflux

2.2: 16 h / 0 - 20 °C

3.1: potassium carbonate / ethanol / 20 °C

4.1: sodium hydroxide / ethylene glycol / 1 h / 130 °C / Schlenk technique

With hydroxylamine; potassium carbonate; sodium hydroxide; diazomethyl-trimethyl-silane; In ethanol; water monomer; ethylene glycol; toluene;

DOI:10.1021/jacs.1c12463

upstream raw materials:

2-(4-cyano-phenyl)-propionic acid

Refernces

• 1、 -. "Leukotriene biosynthesis inhibitors". . . Retrieved 2008/06/13.