3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole

Base Information

Chemical Name:3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole
CAS No.:146993-12-6
Molecular Formula:C₁₃H₁₅N₃O*ClH
Molecular Weight:265.743
Hs Code.:
DSSTox Substance ID:DTXSID20932995
Mol file:146993-12-6.mol

Synonyms:3-amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole;BRL 56905;BRL-56905

Suppliers and Price of 3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole

Chemical Property:

Vapor Pressure:5.65E-11mmHg at 25°C
Boiling Point:521.5°Cat760mmHg
Flash Point:269.2°C
PSA：85.89000
Density:g/cm³
LogP:3.46930
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:265.0981898
Heavy Atom Count:18
Complexity:320

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(CC1N)C3=C(N2)C=CC(=C3)C(=O)N.Cl
Uses 3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole is used in the preparation of tetrahydrocarbazole derivatives that are used as β3-adrenoceptor agonists

Technology Process of 3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole

There total 7 articles about 3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 147009-20-9,147009-39-0,147009-40-3
(6-Carbamoyl-2,3,4,9-tetrahydro-1H-carbazol-3-yl)-carbamic acid tert-butyl ester

: 146993-12-6
BRL 56905 hydrochloride

Guidance literature:: With hydrogenchloride; Yield given;
DOI:10.1021/jm00065a015

Reference yield:

: 6850-65-3
p-hydroxycyclohexylamine

: 146993-12-6
BRL 56905 hydrochloride

Guidance literature:: Multi-step reaction with 7 steps

2: 67 percent / pyridinium chlorochromate

3: 60 percent / AcOH, AcONa

4: N₂H₄*H₂O

6: H₂O₂, NaOH

7: HCl

With hydrogenchloride; sodium hydroxide; dihydrogen peroxide; sodium acetate; hydrazine hydrate; acetic acid; pyridinium chlorochromate;
DOI:10.1021/jm00065a015

Reference yield:

: 147008-87-5
(±)-3-amino-2,3,4,9-tetrahydro-1H-carbazole-6-carbonitrile

: 146993-12-6
BRL 56905 hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

2: H₂O₂, NaOH

3: HCl

With hydrogenchloride; sodium hydroxide; dihydrogen peroxide;
DOI:10.1021/jm00065a015