Technology Process of Guanosine, 2'-deoxy-N-(phenylacetyl)-
There total 19 articles about Guanosine, 2'-deoxy-N-(phenylacetyl)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
(E)-2-nitrobenzaldehyde oxime; N,N,N',N'-tetramethylguanidine;
In
1,4-dioxane; acetonitrile;
for 2.5h;
Product distribution;
Ambient temperature;
influence of other solvent on approximate rates of removal of aryl protecting groups; action of K2CO3 on protected 2'-deoxyguanosine derivative in aq.dioxane solution; stability of protected 2'-deoxyguanosine derivative in pyridine solution;
- Guidance literature:
-
With
(E)-2-nitrobenzaldehyde oxime; N,N,N',N'-tetramethylguanidine;
In
1,4-dioxane; acetonitrile;
for 1.5h;
Product distribution;
Ambient temperature;
influence of other solvent on approximate rates of removal of aryl protecting groups;action of K2CO3 on protected 2'-deoxyguanosine derivative in aq.dioxane solution; stability of protected 2'-deoxyguanosine derivative in pyridine solution;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: pyridine / 0.5 h / Ambient temperature
2: N-hydroxybenzotriazole, pyridine / acetonitrile / 0 - 25 °C
With
pyridine; benzotriazol-1-ol;
In
acetonitrile;
DOI:10.1002/anie.199706471