7,12-Dimethylbenz(a)anthracene-deoxyadenosine adduct

Base Information

• Chemical Name: 7,12-Dimethylbenz(a)anthracene-deoxyadenosine adduct
• CAS No.: 99745-71-8
• Molecular Formula: C₃₀H₃₁N₅O₆
• Molecular Weight: 557.606
• Mol file: 99745-71-8.mol

Synonyms:Dmba-dado;Adenosine, 2-deoxy-N-(1,2,3,4-tetrahydro-2,3,4-trihydroxy-7,12-dimethylbenz(a)anthracen-1-yl)-, (1alpha,2beta,3beta,4alpha)-;(1alpha,2beta,3beta,4alpha)-2-Deoxy-N-(1,2,3,4-tetrahydro-2,3,4-trihydroxy-7,12-dimethylbenz(a)anthracen-1-yl)adenosine;

Chemical Property of 7,12-Dimethylbenz(a)anthracene-deoxyadenosine adduct

Chemical Property:

• Boiling Point: 926.3°Cat760mmHg
• Flash Point: 514°C
• Density: 1.66g/cm³

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7,12-Dimethylbenz(a)anthracene-deoxyadenosine adduct

There total 12 articles about 7,12-Dimethylbenz(a)anthracene-deoxyadenosine adduct which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2'-deoxyadenosine-5'-monophosphoric acid (653-63-4) → (1S,2S,3R,4S)-1-[9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ylamino]-7,12-dimethyl-1,2,3,4-tetrahydro-benzo[a]anthracene-2,3,4-triol (99745-71-8,110044-83-2,138332-02-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Tris-HCl-buffer / acetone; diethyl ether; tetrahydrofuran / 37 °C

2: alkaline phosphatase

With tris-HCl-buffer; In tetrahydrofuran; diethyl ether; acetone;

DOI:10.1021/jo00013a020

Reference yield:

2'-deoxyadenosine-5'-monophosphoric acid (653-63-4) → (1S,2R,3S,4R)-1-[9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ylamino]-7,12-dimethyl-1,2,3,4-tetrahydro-benzo[a]anthracene-2,3,4-triol (99745-71-8,110044-83-2,138332-02-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Tris-HCl-buffer / acetone; diethyl ether; tetrahydrofuran / 37 °C

2: alkaline phosphatase

With tris-HCl-buffer; In tetrahydrofuran; diethyl ether; acetone;

DOI:10.1021/jo00013a020

Reference yield:

2'-deoxyadenosine-5'-monophosphoric acid (653-63-4) → (1R,2S,3R,4S)-1-[9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ylamino]-7,12-dimethyl-1,2,3,4-tetrahydro-benzo[a]anthracene-2,3,4-triol (99745-71-8,110044-83-2,138332-02-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Tris-HCl-buffer / acetone; diethyl ether; tetrahydrofuran / 37 °C

2: alkaline phosphatase

With tris-HCl-buffer; In tetrahydrofuran; diethyl ether; acetone;

DOI:10.1021/jo00013a020

upstream raw materials:

Phosphoric acid mono-{(2R,3S,5R)-3-hydroxy-5-[6-(2,3,4-trihydroxy-7,12-dimethyl-1,2,3,4-tetrahydro-benzo[a]anthracen-1-ylamino)-purin-9-yl]-tetrahydro-furan-2-ylmethyl} ester

7,12-dimethylbenz[a]anthracene anti-diol epoxide

2'-deoxyadenosine-5'-monophosphoric acid