1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4,5,6-tris(phenylmethoxy)-, phenylmethyl ester, (3R,4R,5R,6S)-

Base Information

Chemical Name:1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4,5,6-tris(phenylmethoxy)-, phenylmethyl ester, (3R,4R,5R,6S)-
CAS No.:924895-17-0
Molecular Formula:C35H37NO6
Molecular Weight:567.682
Hs Code.:

Synonyms:

Suppliers and Price of 1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4,5,6-tris(phenylmethoxy)-, phenylmethyl ester, (3R,4R,5R,6S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4,5,6-tris(phenylmethoxy)-, phenylmethyl ester, (3R,4R,5R,6S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4,5,6-tris(phenylmethoxy)-, phenylmethyl ester, (3R,4R,5R,6S)-

There total 6 articles about 1H-Azepine-1-carboxylic acid, hexahydro-3-hydroxy-4,5,6-tris(phenylmethoxy)-, phenylmethyl ester, (3R,4R,5R,6S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 924895-16-9
(3R,4R,5R,6S)-3-hydroxy-4,5,6-tribenzyloxyazepane

: 501-53-1,94274-21-2
benzyl chloroformate

: 924895-17-0
(3S,4R,5R,6R)-benzyl 3,4,5-tris(benzyloxy)-6-hydroxyazepane-1-carboxylate

Guidance literature:: With potassium hydrogencarbonate; In water; ethyl acetate; at 20 ℃;
DOI:10.1039/b610377d

Reference yield: 45.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 6-azido-2,3,4-tri-O-benzyl-6-deoxy-α,β-D-glucopyranose

: 924895-17-0
(3S,4R,5R,6R)-benzyl 3,4,5-tris(benzyloxy)-6-hydroxyazepane-1-carboxylate

Guidance literature:: 6-azido-2,3,4-tri-O-benzyl-6-deoxy-α,β-D-glucopyranose; In tetrahydrofuran; at 40 ℃;

With sodium cyanoborohydride; acetic acid; at 20 ℃; for 14h;

benzyl chloroformate; With potassium carbonate; In water; ethyl acetate; at 0 - 20 ℃;
DOI:10.1039/c3cc46646a

Reference yield:

: C₄₅H₄₄N₃O₅P

: 924895-17-0
(3S,4R,5R,6R)-benzyl 3,4,5-tris(benzyloxy)-6-hydroxyazepane-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 3.33 g / sodium cyanoborohydride / acetic acid / 6 h / 20 °C

2: 92 percent / KHCO₃ / H₂O; ethyl acetate / 20 °C

With sodium cyanoborohydride; potassium hydrogencarbonate; In water; acetic acid; ethyl acetate;
DOI:10.1039/b610377d