2H-Pyrimido(4,5-e)-1,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide

Base Information

Chemical Name:2H-Pyrimido(4,5-e)-1,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide
CAS No.:74051-77-7
Molecular Formula:C₆H₉N₅O₂S₂
Molecular Weight:247.302
Hs Code.:
NSC Number:77525
UNII:RF750HH1YF
DSSTox Substance ID:DTXSID50224976
Nikkaji Number:J87.040D
Wikidata:Q83103825
Mol file:74051-77-7.mol

Synonyms:74051-77-7;NSC77525;2H-Pyrimido(4,5-e)-1,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide;RF750HH1YF;NSC-77525;8-Amino-6-methylthio-3,4-dihydro-1,2H-pyrimido-1,2,4-(4,5-e)thiadiazine 1,1-dioxide;2H-Pyrimido(4,5-e)-1,2,4-thiadiazin-8-amine, 3,4-dihydro-6-(methylthio)-, 1,1-dioxide;2H-Pyrimido[4,5-e]-1,2,4-thiadiazin-8-amine, 3,4-dihydro-6-(methylthio)-, 1,1-dioxide;3,4-Dihydro-8-amino-6-methylthio-2H-pyrimido(4,5-E)-1,2,4-thiadiazine 1,1-dioxide;NSC 77525;BRN 1009439;2H-Pyrimido[4,5-e]-1,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide;8-Amino-6-methylthio-3,4-dihydro-1,2H-pyrimido-1,2,4-[4,5-e]thiadiazine 1,1-dioxide;UNII-RF750HH1YF;6-methylsulfanyl-1,1-dioxo-3,4-dihydro-2H-pyrimido[4,5-e][1,2,4]thiadiazin-8-amine;NCIOpen2_004144;DTXSID50224976;WLN: T66 BSWM EM GN INT&J HS1 JZ;8-Amino-6-methylthio-3,2H-pyrimido-1,2,4-[4,5-e]thiadiazine 1,1-dioxide;2H-Pyrimido[4,2,4-thiadiazin-8-amine, 3,4-dihydro-6-(methylthio)-, 1,1-dioxide;2H-Pyrimido[4,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide;6-(Methylthio)-1,1-dioxido-3,4-dihydro-2H-pyrimido[4,5-e][1,2,4]thiadiazin-8-ylamine;6-(Methylthio)-3,4-dihydro-2H-pyrimido[4,5-e][1,2,4]thiadiazin-8-amine 1,1-dioxide

Suppliers and Price of 2H-Pyrimido(4,5-e)-1,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2H-Pyrimido(4,5-e)-1,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide

Chemical Property:

Vapor Pressure:2.11E-12mmHg at 25°C
Boiling Point:556.1°Cat760mmHg
Flash Point:290.1°C
PSA：143.68000
Density:1.74g/cm³
LogP:1.57080
XLogP3:-0.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:1
Exact Mass:247.01976689
Heavy Atom Count:15
Complexity:329

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NC(=C2C(=N1)NCNS2(=O)=O)N

Technology Process of 2H-Pyrimido(4,5-e)-1,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide

There total 2 articles about 2H-Pyrimido(4,5-e)-1,2,4-thiadiazine, 3,4-dihydro-8-amino-6-methylthio-, 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74039-26-2
8-Amino-6-methylthio-1.2.4-pyrimido-<4.5-e>thiadiazin-1.1-dioxyd

: 74051-77-7
8-Amino-3.4-dihydro-6-methylthio-1.2.4-pyrimido-<4.5-e>thiadiazin-1.1-dioxid

Guidance literature:: With sodium tetrahydroborate; In water;
DOI:10.1021/jo01043a010

Reference yield:

: 51461-76-8
4,6-Diamino-2-methylthio-pyrimidin-5-sulfonamid

: 74051-77-7
8-Amino-3.4-dihydro-6-methylthio-1.2.4-pyrimido-<4.5-e>thiadiazin-1.1-dioxid

Guidance literature:: Multi-step reaction with 2 steps

1: 2 h / 120 - 130 °C

2: NaBH₄ / H₂O

With sodium tetrahydroborate; In water;
DOI:10.1021/jo01043a010