N-Hydroxypicolinimidamide

Base Information

• Chemical Name: N-Hydroxypicolinimidamide
• CAS No.: 1772-01-6
• Molecular Formula: C6H7N3O
• Molecular Weight: 137.141
• Hs Code.: 29333990
• European Community (EC) Number: 626-840-3
• Nikkaji Number: J948.612G
• Mol file: 1772-01-6.mol

Synonyms:1772-01-6;N-Hydroxypicolinimidamide;Picolinamidoxime;Pyridine-2-carboxamidoxime;N'-hydroxypyridine-2-carboximidamide;N-hydroxypyridine-2-carboximidamide;(Z)-N'-hydroxypicolinimidamide;N-Hydroxy-pyridine-2-carboxamidine;2-pyridylamid Oxime;MFCD00085159;2-Pyridineamidoxime;Pyridin-2-amidoxim;N'-hydroxypicolinimidamide;(Z)-N'-hydroxypicolinamidine;n-hydroxy pyridine-carboxamidine;N-hydroxy-2-pyridinecarboximidamide;N'-hydroxy-2-pyridinecarboximidamide;AKOS030231501;SY073648;FT-0682825;FT-0693753;P2590;W16237

Chemical Property of N-Hydroxypicolinimidamide

Chemical Property:

• Melting Point: 120-124 °C(lit.)
• Refractive Index: 1.6910 (estimate)
• Boiling Point: 198.964 °C at 760 mmHg
• PKA: 13.61±0.50(Predicted)
• Flash Point: 74.131 °C
• PSA: 71.50000
• Density: 1.32 g/cm³
• LogP: 0.87640
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 137.058911855
• Heavy Atom Count: 10
• Complexity: 135

Purity/Quality:

97% ^*data from raw suppliers

(Z)-N''-Hydroxypicolinimidamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=NC(=C1)C(=NO)N
• Uses: 2-Pyridylamide oxime is a synthetic intermediate useful for pharmaceutical synthesis.

Technology Process of N-Hydroxypicolinimidamide

There total 26 articles about N-Hydroxypicolinimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-Cyanopyridine (100-70-9,1232006-36-8) → 2-pyridylamidoxime (1772-01-6)

Guidance literature:

With hydroxyamino hydrochloride; triethylamine; In ethanol; for 3h; Reflux;

Reference yield: 93.0%

2-Cyanopyridine (100-70-9,1232006-36-8) → (Z)-N'-hydroxy-pyridine-2-carboxamidine (1772-01-6)

Guidance literature:

With hydroxylamine hydrochloride;

Reference yield: 93.0%

→ 2-pyridylamidoxime (1772-01-6)

Guidance literature:

upstream raw materials:

2-Cyanopyridine

pyridine-2-acetonitrile

pyridine-2-carbaldehyde

2-pyridinealdoxime

Downstream raw materials:

3-([2]pyridyl-[1,2,4]oxadiazol-5-yl)-propionic acid

3-(pyridin-2-yl)-5-(2-aminophenyl)-1,2,4-oxadiazole