5-Allyl-6-chloro-2-methylpyrimidin-4-amine

Base Information

Chemical Name:5-Allyl-6-chloro-2-methylpyrimidin-4-amine
CAS No.:85826-34-2
Molecular Formula:C₈H₁₀ClN₃
Molecular Weight:183.64
Hs Code.:
DSSTox Substance ID:DTXSID601006403
Wikidata:Q83002123

Synonyms:5-allyl-6-chloro-2-methylpyrimidin-4-amine;85826-34-2;C8H10ClN3;BRN 4987743;Oprea1_281663;6-Chloro-2-methyl-5-(2-propenyl)-4-pyrimidinamine;4-Pyrimidinamine, 6-chloro-2-methyl-5-(2-propenyl)-;DTXSID601006403;STK067736;AKOS022084230;6-chloro-2-methyl-5-(prop-2-en-1-yl)pyrimidin-4-amine;6-Chloro-2-methyl-5-(prop-2-en-1-yl)pyrimidin-4(3H)-imine

Suppliers and Price of 5-Allyl-6-chloro-2-methylpyrimidin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-Allyl-6-chloro-2-methylpyrimidin-4-amine

Chemical Property:

Vapor Pressure:0.00092mmHg at 25°C
Boiling Point:303.6°Cat760mmHg
Flash Point:137.4°C
PSA：51.80000
Density:1.217g/cm³
LogP:2.33030
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:183.0563250
Heavy Atom Count:12
Complexity:162

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=C(C(=N1)Cl)CC=C)N

Technology Process of 5-Allyl-6-chloro-2-methylpyrimidin-4-amine

There total 3 articles about 5-Allyl-6-chloro-2-methylpyrimidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.1%

: 85826-33-1
5-Allyl-2-methyl-4,6-dichloropyrimidine

: 85826-34-2
5-Allyl-4-amino-2-methyl-6-chloropyrimidine

Guidance literature:: With ammonia; In ethanol; for 6h; Heating;
DOI:10.1007/BF00765165

Reference yield:

: 2049-80-1
(2-propenyl)propanedioic acid diethyl ester

: 85826-34-2
5-Allyl-4-amino-2-methyl-6-chloropyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 72.3 percent / CH₃ONa / methanol / 10 h / Heating

2: 60.6 percent / phosphoryl chloride, dimethylaniline / 7 h

3: 50.1 percent / NH₃ / ethanol / 6 h / Heating

With ammonia; sodium methylate; 2,3-Dimethylaniline; trichlorophosphate; In methanol; ethanol;
DOI:10.1007/BF00765165

Reference yield:

: 85826-32-0
5-Allyl-2-methyl-4,6-dihydroxypyrimidine

: 85826-34-2
5-Allyl-4-amino-2-methyl-6-chloropyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 60.6 percent / phosphoryl chloride, dimethylaniline / 7 h

2: 50.1 percent / NH₃ / ethanol / 6 h / Heating

With ammonia; 2,3-Dimethylaniline; trichlorophosphate; In ethanol;
DOI:10.1007/BF00765165