Pyrrolo[3,2-e]indole, 1,2,3,6-tetrahydro-1,8-bis[(methoxymethoxy)methyl]-6-[(4-methylphenyl) sulfonyl]-5-(phenylmethoxy)-3-(phenylmethyl)-

Base Information

Chemical Name:Pyrrolo[3,2-e]indole, 1,2,3,6-tetrahydro-1,8-bis[(methoxymethoxy)methyl]-6-[(4-methylphenyl) sulfonyl]-5-(phenylmethoxy)-3-(phenylmethyl)-
CAS No.:925463-59-8
Molecular Formula:C37H40N2O7S
Molecular Weight:656.8
Hs Code.:

Pyrrolo[3,2-e]indole,
1,2,3,6-tetrahydro-1,8-bis[(methoxymethoxy)methyl]-6-[(4-methylphenyl)
sulfonyl]-5-(phenylmethoxy)-3-(phenylmethyl)-

Synonyms:

Suppliers and Price of Pyrrolo[3,2-e]indole, 1,2,3,6-tetrahydro-1,8-bis[(methoxymethoxy)methyl]-6-[(4-methylphenyl) sulfonyl]-5-(phenylmethoxy)-3-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Pyrrolo[3,2-e]indole, 1,2,3,6-tetrahydro-1,8-bis[(methoxymethoxy)methyl]-6-[(4-methylphenyl) sulfonyl]-5-(phenylmethoxy)-3-(phenylmethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Pyrrolo[3,2-e]indole, 1,2,3,6-tetrahydro-1,8-bis[(methoxymethoxy)methyl]-6-[(4-methylphenyl) sulfonyl]-5-(phenylmethoxy)-3-(phenylmethyl)-

There total 16 articles about Pyrrolo[3,2-e]indole, 1,2,3,6-tetrahydro-1,8-bis[(methoxymethoxy)methyl]-6-[(4-methylphenyl) sulfonyl]-5-(phenylmethoxy)-3-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 925463-58-7
trifluoro-methanesulfonic acid 4-(2-benzylamino-1-methoxymethoxymethyl-ethyl)-7-benzyloxy-3-methoxymethoxymethyl-1-(toluene-4-sulfonyl)-1H-indol-5-yl ester

: 925463-59-8
3-benzyl-5-benzyloxy-1,8-bis-methoxymethoxymethyl-6-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-3,6-diaza-as-indacene

Guidance literature:: With di-tert-butylbiphenylphosphine; caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; for 40h;
DOI:10.1021/jo062064j

Reference yield:

: (2E,4E)-1,6-Bis-methoxymethoxy-hexa-2,4-diene

: 925463-59-8
3-benzyl-5-benzyloxy-1,8-bis-methoxymethoxymethyl-6-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-3,6-diaza-as-indacene

Guidance literature:: Multi-step reaction with 8 steps

1: CH₂Cl₂ / 24 h / 9308660 Torr

2: 0.860 g / 1,8-diazabicyclo[5.4.0]undec-7-ene / CH₂Cl₂ / 0.5 h

3: 98 percent / sodium hydride / tetrahydrofuran / 0.67 h / 0 - 20 °C

4: osmium tetroxide; 2,6-lutidine; N-methylmorpholine N-oxide / tetrahydrofuran; H₂O

5: sodium periodate on silica gel / CH₂Cl₂ / 2.5 h

6: 0.790 g / triethylamine; methanesulfonyl chloride / tetrahydrofuran / 0.33 h

7: 70 percent / sodium cyanoborohydride / methanol / 3 h / 20 °C

8: 82 percent / di-tert-butylbiphenylphosphine; Cs₂CO₃ / tris(dibenzylideneacetone)dipalladium⁽⁰⁾ / dioxane / 40 h

With 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide; di-tert-butylbiphenylphosphine; sodium hydride; sodium cyanoborohydride; caesium carbonate; methanesulfonyl chloride; 4-methylmorpholine N-oxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; 1: Diels-Alder reaction / 8: Buchwald-Hartwig amidation;
DOI:10.1021/jo062064j

Reference yield:

: 221615-94-7
3-(benzyloxy)-4-nitrophenol

: 925463-59-8
3-benzyl-5-benzyloxy-1,8-bis-methoxymethoxymethyl-6-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-3,6-diaza-as-indacene

Guidance literature:: Multi-step reaction with 11 steps

1: sodium borohydride; nickel(II) chloride hexahydrate / tetrahydrofuran; methanol

2: 84 percent / pyridine / CH₂Cl₂ / 4 h / 20 °C

3: 96 percent / sodium periodate on silica gel / CH₂Cl₂ / 4 h

4: CH₂Cl₂ / 24 h / 9308660 Torr

5: 0.860 g / 1,8-diazabicyclo[5.4.0]undec-7-ene / CH₂Cl₂ / 0.5 h

6: 98 percent / sodium hydride / tetrahydrofuran / 0.67 h / 0 - 20 °C

7: osmium tetroxide; 2,6-lutidine; N-methylmorpholine N-oxide / tetrahydrofuran; H₂O

8: sodium periodate on silica gel / CH₂Cl₂ / 2.5 h

9: 0.790 g / triethylamine; methanesulfonyl chloride / tetrahydrofuran / 0.33 h

10: 70 percent / sodium cyanoborohydride / methanol / 3 h / 20 °C

11: 82 percent / di-tert-butylbiphenylphosphine; Cs₂CO₃ / tris(dibenzylideneacetone)dipalladium⁽⁰⁾ / dioxane / 40 h

With pyridine; 2,6-dimethylpyridine; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; di-tert-butylbiphenylphosphine; sodium hydride; sodium cyanoborohydride; caesium carbonate; methanesulfonyl chloride; 4-methylmorpholine N-oxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; nickel dichloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; 4: Diels-Alder reaction / 11: Buchwald-Hartwig amidation;
DOI:10.1021/jo062064j