7-Oxa-8-azabicyclo[4.2.1]nonan-4-one, 3-hydroxy-8-methyl-2-(phenylmethoxy)-, (1S,2R,3R,6R)-

Base Information

Chemical Name:7-Oxa-8-azabicyclo[4.2.1]nonan-4-one, 3-hydroxy-8-methyl-2-(phenylmethoxy)-, (1S,2R,3R,6R)-
CAS No.:925545-57-9
Molecular Formula:C15H19NO4
Molecular Weight:277.32
Hs Code.:

Synonyms:

Suppliers and Price of 7-Oxa-8-azabicyclo[4.2.1]nonan-4-one, 3-hydroxy-8-methyl-2-(phenylmethoxy)-, (1S,2R,3R,6R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-Oxa-8-azabicyclo[4.2.1]nonan-4-one, 3-hydroxy-8-methyl-2-(phenylmethoxy)-, (1S,2R,3R,6R)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-Oxa-8-azabicyclo[4.2.1]nonan-4-one, 3-hydroxy-8-methyl-2-(phenylmethoxy)-, (1S,2R,3R,6R)-

There total 10 articles about 7-Oxa-8-azabicyclo[4.2.1]nonan-4-one, 3-hydroxy-8-methyl-2-(phenylmethoxy)-, (1S,2R,3R,6R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 925545-56-8
2-benzyloxy-8-methyl-7-oxa-8-aza-bicyclo[4.2.1]nonane-3,4-diol

: 2-benzyloxy-4-hydroxy-8-methyl-7-oxa-8-aza-bicyclo[4.2.1]nonan-3-one

: 925545-57-9
2-benzyloxy-3-hydroxy-8-methyl-7-oxa-8-aza-bicyclo[4.2.1]nonan-4-one

Guidance literature:: With acetic anhydride; In dimethyl sulfoxide; at 20 ℃; for 60h;
DOI:10.1021/ol062621o

Reference yield:

: 925545-70-6
5,5,11-trimethyl-4,6,10-trioxa-11-aza-tricyclo[7.2.1.0^3,7]dodecan-2-ol

: 925545-57-9
2-benzyloxy-3-hydroxy-8-methyl-7-oxa-8-aza-bicyclo[4.2.1]nonan-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / sodium hydride; tetra-n-butylammonium iodide / tetrahydrofuran / 0 - 20 °C

2: 100 percent / TFA / CH₂Cl₂; H₂O / 1 h / 20 °C

3: 68 percent / acetic anhydride / dimethylsulfoxide / 60 h / 20 °C

With acetic anhydride; tetra-(n-butyl)ammonium iodide; sodium hydride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1021/ol062621o

Reference yield:

: 912642-25-2
oct-7-ene-1,2,3,4,5-pentaol

: 925545-57-9
2-benzyloxy-3-hydroxy-8-methyl-7-oxa-8-aza-bicyclo[4.2.1]nonan-4-one

Guidance literature:: Multi-step reaction with 7 steps

1: 264 mg / anhydrous CuSO₄ / 24 h / 20 °C

2: 97 percent / sodium hydride; tetra-n-butylammonium iodide / tetrahydrofuran / 0 - 20 °C

3: 87 percent Turnov_. / AcOH / H₂O / 9 h / 20 °C

4: NaIO₄; silica gel / H₂O; CH₂Cl₂ / 20 - 80 °C

5: 366 mg / NaHCO₃ / acetonitrile / Heating

6: 100 percent / TFA / CH₂Cl₂; H₂O / 1 h / 20 °C

7: 68 percent / acetic anhydride / dimethylsulfoxide / 60 h / 20 °C

With sodium periodate; acetic anhydride; silica gel; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium hydrogencarbonate; copper(II) sulfate; acetic acid; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; acetonitrile;
DOI:10.1021/ol062621o