4-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]aniline

Base Information

Chemical Name:4-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]aniline
CAS No.:92554-86-4
Molecular Formula:C15H13N3O2
Molecular Weight:267.287
Hs Code.:
DSSTox Substance ID:DTXSID60362494
Nikkaji Number:J1.529.379I
Wikidata:Q82145623
ChEMBL ID:CHEMBL1482872

Synonyms:4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]aniline;92554-86-4;SMR000069078;MLS000058812;4-(5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)aniline;benzenamine, 4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-;Oprea1_335269;CHEMBL1482872;BDBM49260;cid_1380741;DTXSID60362494;HMS2424K13;MFCD00429399;STK520547;AKOS005455479;SDCCGMLS-0006720.P002;BB 0238374;SR-01000197408;SR-01000197408-1;4-[5-(4-Methoxyphenyl)-1,3,4-oxadiazole-2-yl]aniline;[4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]phenyl]amine;4-[5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-yl] -phenylamine

Suppliers and Price of 4-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]aniline

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:267.100776666
Heavy Atom Count:20
Complexity:300

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NN=C(O2)C3=CC=C(C=C3)N

Technology Process of 4-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]aniline

There total 11 articles about 4-[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 62507-51-1
2-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole

: 92554-86-4
2-(4-aminophenyl)-5-(4-methoxyhenyl)-1,3,4-oxadiazole

Guidance literature:: With hydrazine hydrate; palladium on activated charcoal; In ethanol; for 25h; Heating;
DOI:10.1080/10426500600919074

Reference yield: 75.0%

: 3290-99-1
4-methoxybenzoic acid hydrazide

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 92554-86-4
2-(4-aminophenyl)-5-(4-methoxyhenyl)-1,3,4-oxadiazole

Guidance literature:: With trichlorophosphate; Reflux;
DOI:10.1002/jhet.383

Reference yield:

: 92555-33-4
1-(4-methoxybenzoyl)-2-(4-nitrobenzoyl)hydrazine

: 92554-86-4
2-(4-aminophenyl)-5-(4-methoxyhenyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / thionyl chloride / 2 h / Heating

2: 89 percent / hydrazine monohydrate / Pd/C / ethanol / 25 h / Heating

With thionyl chloride; hydrazine hydrate; palladium on activated charcoal; In ethanol;
DOI:10.1080/10426500600919074