Taxa-4(20),11(12)-dien-5alpha,13alpha-diol

Base Information

• Chemical Name: Taxa-4(20),11(12)-dien-5alpha,13alpha-diol
• CAS No.: 357436-25-0
• Molecular Formula: C20H32O2
• Molecular Weight: 304.4669
• DSSTox Substance ID: DTXSID60332112
• Nikkaji Number: J2.611.931F
• Wikidata: Q27104104
• Metabolomics Workbench ID: 28645
• Mol file: 357436-25-0.mol

Synonyms:Taxa-4(20),11(12)-dien-5alpha,13alpha-diol;357436-25-0;taxa-4(20),11-dien-5alpha,13alpha-diol;(1R,3S,5S,8R,13S)-8,12,15,15-tetramethyl-4-methylidenetricyclo[9.3.1.03,8]pentadec-11-ene-5,13-diol;SCHEMBL3512995;CHEBI:30041;DTXSID60332112;LMPR0104390005;Taxa-4(20),11-diene-5alpha,13alpha-diol;(5alpha,13alpha)-taxa-4(20),11-diene-5,13-diol;Q27104104

Chemical Property of Taxa-4(20),11(12)-dien-5alpha,13alpha-diol

Chemical Property:

• Vapor Pressure: 4.25E-09mmHg at 25°C
• Boiling Point: 427.4°Cat760mmHg
• Flash Point: 189.1°C
• Density: 1.05g/cm³
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 304.240230259
• Heavy Atom Count: 22
• Complexity: 516

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C2CCC3(CCC(C(=C)C3CC(C2(C)C)CC1O)O)C
• Isomeric SMILES: CC1=C2CC[C@@]3(CC[C@@H](C(=C)[C@H]3C[C@@H](C2(C)C)C[C@@H]1O)O)C

Technology Process of Taxa-4(20),11(12)-dien-5alpha,13alpha-diol

There total 5 articles about Taxa-4(20),11(12)-dien-5alpha,13alpha-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

5α,13α-bis(triethylsilyloxy)-taxa-4(20),11(12)-diene (1042945-91-4) → taxa-4(20),11(12)-diene-5α,13α-diol (357436-25-0)

Guidance literature:

With pyridine; pyridine hydrogenfluoride; at 0 - 20 ℃;

DOI:10.1016/j.tet.2008.04.008

Reference yield: 83.0%

5α,13α-bis[diethyl(isopropyl)silyloxy]-taxa-4(20),11(12)-diene (1042946-01-9) → taxa-4(20),11(12)-diene-5α,13α-diol (357436-25-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 55 ℃;

DOI:10.1016/j.tet.2008.04.008

Reference yield: 51.0%

5α-acetoxytaxa-4(20),11(12)-dien-13-one (1581285-71-3) → taxa-4(20),11(12)-diene-5α,13α-diol (357436-25-0)

Guidance literature:

With diisobutylaluminium hydride; In hexane; toluene; at -78 - -20 ℃; for 1.5h; Inert atmosphere;

DOI:10.1021/ja501782r

upstream raw materials:

5α,13α-bis(triethylsilyloxy)-taxa-4(20),11(12)-diene

5α,13α-bis[diethyl(isopropyl)silyloxy]-taxa-4(20),11(12)-diene

taxadiene

5α-acetoxytaxa-4(20),11(12)-dien-13-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 357436-25-0 (3xi,5alpha,13alpha)-taxa-4(20),11-diene-5,13-diol

Send

Send

Metric Ton KG G Pound L ML

Send

Send