3-Hydroxybicyclo(4.2.0)octa-1,3,5-triene-7,8-dione

Base Information

Chemical Name:3-Hydroxybicyclo(4.2.0)octa-1,3,5-triene-7,8-dione
CAS No.:75833-48-6
Molecular Formula:C₈H₄O₃
Molecular Weight:148.118
Hs Code.:
NSC Number:369774
UNII:MRJ3Q7I4P7
DSSTox Substance ID:DTXSID90226732
Wikidata:Q83106237

Synonyms:75833-48-6;4-Hydroxybenzocyclobutene-1,2-dione;MRJ3Q7I4P7;3-Hydroxybicyclo(4.2.0)octa-1,3,5-triene-7,8-dione;NSC369774;UNII-MRJ3Q7I4P7;NSC 369774;NSC-369774;3-Hydroxybicyclo[4.2.0]octa-1,3,5-triene-7,8-dione;4-hydroxybicyclo[4.2.0]octa-1(6),2,4-triene-7,8-dione;DTXSID90226732;BICYCLO(4.2.0)OCTA-1,3,5-TRIENE-7,8-DIONE, 3-HYDROXY-

Suppliers and Price of 3-Hydroxybicyclo(4.2.0)octa-1,3,5-triene-7,8-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-Hydroxybicyclo(4.2.0)octa-1,3,5-triene-7,8-dione

Chemical Property:

Vapor Pressure:6.34E-06mmHg at 25°C
Boiling Point:367.7°Cat760mmHg
Flash Point:190.4°C
Density:1.606g/cm³
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:148.016043985
Heavy Atom Count:11
Complexity:221

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1O)C(=O)C2=O

Technology Process of 3-Hydroxybicyclo(4.2.0)octa-1,3,5-triene-7,8-dione

There total 4 articles about 3-Hydroxybicyclo(4.2.0)octa-1,3,5-triene-7,8-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 82431-25-2
2,2-difluoro-4-hydroxybenzocyclobutenone

: 75833-48-6
4-hydroxybenzocyclobutene-1,2-dione

Guidance literature:: With sulfuric acid; acetic acid; at 90 ℃; for 3h;
DOI:10.1021/jo00141a002

Reference yield: 70.0%

: 41634-29-1
4-methoxybenzocyclobutene-1,2-dione

: 75833-48-6
4-hydroxybenzocyclobutene-1,2-dione

Guidance literature:: With hydrogen bromide; for 4.5h; Heating;

Reference yield:

: 14161-12-7
6-methoxy-2,3-dihydro-phthalazine-1,4-dione

: 75833-48-6
4-hydroxybenzocyclobutene-1,2-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 55 percent / lead tetra-acetate / CH₂Cl₂ / 3 h / Ambient temperature

2: 83 percent / 1.5 h / 450 °C / 0.01 Torr

3: 70 percent / aq.HBr / 4.5 h / Heating

With lead(IV) acetate; hydrogen bromide; In dichloromethane;