Chemical Property of Isoliensinine
Chemical Property:
- Vapor Pressure:1.32E-21mmHg at 25°C
- Melting Point:69-71℃
- Refractive Index:1.618
- Boiling Point:723.1 °C at 760 mmHg
- PKA:9.28±0.45(Predicted)
- Flash Point:391.1 °C
- PSA：83.86000
- Density:1.218 g/cm3
- LogP:6.33510
- Storage Temp.:2-8°C(protect from light)
- XLogP3:6.4
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:8
- Rotatable Bond Count:9
- Exact Mass:610.30428706
- Heavy Atom Count:45
- Complexity:917
- Purity/Quality:
-
99%, *data from raw suppliers
Isoliensinine *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)O)O)OC
- Isomeric SMILES:CN1CCC2=CC(=C(C=C2[C@H]1CC3=CC=C(C=C3)OC)OC4=C(C=CC(=C4)C[C@@H]5C6=CC(=C(C=C6CCN5C)OC)O)O)OC
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Description
Tomita and his co-workers have obtained this bisisoquinoline alkaloid from the
embryo of the seeds of Nelumbo nucifera Gaertn. The base has [α]29D + 49.3°
(Me2CO) and - 43.3° (CHC13 ). The hydrochloride tetrahydrate forms colourless
crystals, m.p. l85-6°C (dry); the perchlorate monohydrate has m.p. 200-3°C
(dry); [α]22D - 70° (Me2CO) and the styphnate of the O,O-dimethyl ether, also
crystalline, has m.p. l33-5°C; [α]27D - 81.5° (Me2CO). Three methoxyl, two
hydroxyl and two methylimino groups are present.
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Uses
(+)-Isoliensinine is an alkaloid which displays activation of AMP-activated kinase and regulation of PPARγ receptors.
