(R)-(-)-N(ALPHA)-BENZYL-N(BETA)-BOC-(D)-HYDRAZINOVALINE

Base Information

Chemical Name:(R)-(-)-N(ALPHA)-BENZYL-N(BETA)-BOC-(D)-HYDRAZINOVALINE
CAS No.:313672-19-4
Molecular Formula:C₁₇H₂₆N₂O₄
Molecular Weight:322.404
Hs Code.:
Mol file:313672-19-4.mol

Synonyms:Hydrazinecarboxylicacid, 2-[(1R)-1-carboxy-2-methylpropyl]-2-(phenylmethyl)-,1-(1,1-dimethylethyl) ester (9CI)

Suppliers and Price of (R)-(-)-N(ALPHA)-BENZYL-N(BETA)-BOC-(D)-HYDRAZINOVALINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R)-(-)-NALPHA-BENZYL-NBETA-BOC-D-HYDRAZINOVALINE 95.00%
5MG
$ 496.12

Total 3 raw suppliers

Chemical Property of (R)-(-)-N(ALPHA)-BENZYL-N(BETA)-BOC-(D)-HYDRAZINOVALINE

Chemical Property:

Melting Point:115-121 °C
Boiling Point:°Cat760mmHg
Flash Point:°C
Density:g/cm³
Storage Temp.:0-6°C

Purity/Quality:

99% ^*data from raw suppliers

(R)-(-)-NALPHA-BENZYL-NBETA-BOC-D-HYDRAZINOVALINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:

Useful:

Technology Process of (R)-(-)-N(ALPHA)-BENZYL-N(BETA)-BOC-(D)-HYDRAZINOVALINE

There total 8 articles about (R)-(-)-N(ALPHA)-BENZYL-N(BETA)-BOC-(D)-HYDRAZINOVALINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 150884-56-3,158807-35-3
N-tert-butyloxycarbonyl-3-(4-cyanophenyl)oxaziridine

: 98575-68-9
(R)-N-benzylvaline

: 313672-19-4
2-(N-benzyl-N'-tert-butoxycarbonyl-hydrazino)-3-methyl-butyric acid

Guidance literature:: (R)-N-benzylvaline; With N-benzyl-trimethylammonium hydroxide; In methanol; at 20 ℃; for 0.5h;

N-tert-butyloxycarbonyl-3-(4-cyanophenyl)oxaziridine; In dichloromethane; at -35 - 20 ℃; for 17h;
DOI:10.1021/jm0606600

Reference yield: 68.0%

: 15363-84-5
(S)-2-(benzylamino)-3-methylbutanoic acid

: 150884-56-3,158807-35-3
N-tert-butyloxycarbonyl-3-(4-cyanophenyl)oxaziridine

: 188777-46-0,313672-19-4
(S)-2-{1-benzyl-2-[(tert-butoxy)carbonyl]hydrazino}-3-methylbutanoic acid

Guidance literature:: With tetraethylammonium hydroxide; 1.) MeOH, 2.) CH₂Cl₂;
DOI:10.1002/chem.19970031019

Reference yield:

: 1070-19-5
N-(tert-butyloxycarbonyl) azide

: 188777-46-0,313672-19-4
(S)-2-{1-benzyl-2-[(tert-butoxy)carbonyl]hydrazino}-3-methylbutanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / diethyl ether

2: 75 percent / toluene / 17 h / Heating

3: LiMCPBA / CH₂Cl₂ / 2 h / -78 °C

4: 68 percent / Et₄NOH / 1.) MeOH, 2.) CH₂Cl₂

With LiMCPBA; tetraethylammonium hydroxide; In diethyl ether; dichloromethane; toluene;
DOI:10.1002/chem.19970031019