OLANZAPINE N-OXIDE

Base Information

Chemical Name:OLANZAPINE N-OXIDE
CAS No.:174794-02-6
Molecular Formula:C₁₇H₂₀N₄OS
Molecular Weight:328.438
Hs Code.:29349990
Mol file:174794-02-6.mol

Synonyms:LY 170238;Olanzapine-N-oxide

Suppliers and Price of OLANZAPINE N-OXIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
OlanzapineN-Oxide
2.5mg
$ 180.00

TRC
OlanzapineN-Oxide
25mg
$ 1390.00

Medical Isotopes, Inc.
OlanzapineN-Oxide
2.5 mg
$ 875.00

Biosynth Carbosynth
Olanzapine N-oxide
100 mg
$ 1000.00

Biosynth Carbosynth
Olanzapine N-oxide
50 mg
$ 600.00

Biosynth Carbosynth
Olanzapine N-oxide
10 mg
$ 200.00

Biosynth Carbosynth
Olanzapine N-oxide
5 mg
$ 125.00

Biosynth Carbosynth
Olanzapine N-oxide
25 mg
$ 375.00

AvaChem
Olanzapine N-Oxide
10mg
$ 225.00

AvaChem
Olanzapine N-Oxide
5mg
$ 125.00

Total 30 raw suppliers

Chemical Property of OLANZAPINE N-OXIDE

Chemical Property:

Melting Point:214-216°C (dec.)
PKA:7.32±0.20(Predicted)
PSA：75.50000
LogP:2.92210
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

OlanzapineN-Oxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Uses A metabolite of Olanzapine (Olanzapine EP Impurity D).

Technology Process of OLANZAPINE N-OXIDE

There total 6 articles about OLANZAPINE N-OXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.1%

: 132539-06-1
zyprexa

: 174794-02-6
Olanzapine N-Oxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 12 ℃; for 12h;

Reference yield:

: 109-01-3
1-methyl-piperazine

: 174794-02-6
Olanzapine N-Oxide

Guidance literature:: Multi-step reaction with 2 steps

1: toluene; dimethylsulfoxide

2: m-CPBA / CH₂Cl₂

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1016/S0960-894X(96)00567-7

Reference yield:

: 1493-27-2,127723-77-7
ortho-nitrofluorobenzene

: 174794-02-6
Olanzapine N-Oxide

Guidance literature:: Multi-step reaction with 4 steps

1: LiOH / dimethylsulfoxide

2: SnCl₂ / ethanol

3: toluene; dimethylsulfoxide

4: m-CPBA / CH₂Cl₂

With lithium hydroxide; 3-chloro-benzenecarboperoxoic acid; tin(ll) chloride; In ethanol; dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1016/S0960-894X(96)00567-7