1H-Pyrrole-2,5-dicarboxylic acid, 3,4-bis[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]methyl]-, 2-(1,1-dimethylethyl) 5-(phenylmethyl) ester

Base Information

• Chemical Name: 1H-Pyrrole-2,5-dicarboxylic acid, 3,4-bis[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]methyl]-, 2-(1,1-dimethylethyl) 5-(phenylmethyl) ester
• CAS No.: 926913-32-8
• Molecular Formula: C31H47NO12
• Molecular Weight: 625.714
• Mol file: 926913-32-8.mol

Synonyms:

Chemical Property of 1H-Pyrrole-2,5-dicarboxylic acid, 3,4-bis[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]methyl]-, 2-(1,1-dimethylethyl) 5-(phenylmethyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1H-Pyrrole-2,5-dicarboxylic acid, 3,4-bis[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]methyl]-, 2-(1,1-dimethylethyl) 5-(phenylmethyl) ester

There total 3 articles about 1H-Pyrrole-2,5-dicarboxylic acid, 3,4-bis[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]methyl]-, 2-(1,1-dimethylethyl) 5-(phenylmethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

benzyl alcohol (100-51-6,185532-71-2) + 3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole 2,5-dicarboxylic acid 2-tert-butyl ester 5-ethyl ester (492454-09-8) → 3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole-2,5-dicarboxylic acid 2-benzyl ester 5-tert-butyl ester (926913-32-8)

Guidance literature:

With sodium; for 3h; under 0.900072 Torr; Heating;

DOI:10.1002/chem.200600573

Reference yield:

3,4-bis-bromomethyl-1H-pyrrole 2,5-dicarboxylic acid 2-tert-butyl ester 5-ethyl ester (492454-08-7) → 3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole-2,5-dicarboxylic acid 2-benzyl ester 5-tert-butyl ester (926913-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / NEt₃ / CH₂Cl₂ / 24 h / 100 °C

2: 70 percent / sodium / 3 h / 0.9 Torr / Heating

With sodium; triethylamine; In dichloromethane;

DOI:10.1002/chem.200600573

Reference yield:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → 3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole-2,5-dicarboxylic acid 2-benzyl ester 5-tert-butyl ester (926913-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / NEt₃ / CH₂Cl₂ / 24 h / 100 °C

2: 70 percent / sodium / 3 h / 0.9 Torr / Heating

With sodium; triethylamine; In dichloromethane;

DOI:10.1002/chem.200600573

upstream raw materials:

benzyl alcohol

3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole 2,5-dicarboxylic acid 2-tert-butyl ester 5-ethyl ester

3,4-bis-bromomethyl-1H-pyrrole 2,5-dicarboxylic acid 2-tert-butyl ester 5-ethyl ester

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

Downstream raw materials:

C₄₅H₇₈N₄O₁₃Si₂

C₃₃H₅₀N₄O₁₃

3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole-2,5-dicarboxylic acid monobenzyl ester