1-methyl-4-prop-2-ynoxy-benzene

Base Information

• Chemical Name: 1-methyl-4-prop-2-ynoxy-benzene
• CAS No.: 5651-90-1
• Molecular Formula: C10H10 O
• Molecular Weight: 146.189
• Hs Code.: 2909309090
• Mol file: 5651-90-1.mol

Synonyms:Benzene,1-methyl-4-(2-propynyloxy)- (9CI); Ether, 2-propynyl p-tolyl (7CI,8CI);1-Methyl-4-(2-propynyloxy)benzene; 2-Propynyl p-tolyl ether;3-(p-Tolyloxy)propyne; 4-Methylphenyl propargyl ether; 4-Tolyl propargyl ether;NSC 298261; Propargyl p-tolyl ether; p-(Propargyloxy)toluene; p-Methylphenylpropargyl ether; p-Tolyl propargyl ether

Chemical Property of 1-methyl-4-prop-2-ynoxy-benzene

Chemical Property:

• Vapor Pressure: 0.114mmHg at 25°C
• Boiling Point: 227.9°Cat760mmHg
• Flash Point: 84.6°C
• PSA: 9.23000
• Density: 0.997g/cm³
• LogP: 2.00700

Purity/Quality:

99% ^*data from raw suppliers

4-Methyl-phenylpropargylether ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-methyl-4-prop-2-ynoxy-benzene

There total 11 articles about 1-methyl-4-prop-2-ynoxy-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

p-cresol (106-44-5) + propargyl bromide (106-96-7) → 1-methyl-4-(2-propynyloxy)benzene (5651-90-1)

Guidance literature:

With potassium carbonate; In acetone; Reflux;

DOI:10.1016/j.steroids.2010.02.015

Reference yield: 99.0%

p-cresol (106-44-5) + 2-propynyl chloride (624-65-7) → dipropargyl ether (6921-27-3) + 1-methyl-4-(2-propynyloxy)benzene (5651-90-1)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide;

Reference yield: 85.0%

propargyl bromide (106-96-7) + phenol (108-95-2,27073-41-2) → 1-methyl-4-(2-propynyloxy)benzene (5651-90-1)

Guidance literature:

With potassium carbonate; In acetonitrile; for 12h; Reflux;

DOI:10.1021/acs.orglett.8b03159

upstream raw materials:

p-cresol

2-propynyl chloride

propargyl bromide

4-p-tolyloxymethyl-1,2,3-selenadiazole

Downstream raw materials:

(4-methylphenoxy)propan-2-one

1-methyl-4-(3-deuterio-2-propynyloxy)benzene

3-(p-tolyloxy)-2-phenylsulfinyl-1-propene

6-methyl-2H-chromene