Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3-(4H)-quinazolinyl)butyl)-4-(4-methylphenyl)-

Base Information

Chemical Name:Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3-(4H)-quinazolinyl)butyl)-4-(4-methylphenyl)-
CAS No.:83409-17-0
Molecular Formula:C₃₃H₃₈N₄O₅
Molecular Weight:570.689
Hs Code.:
DSSTox Substance ID:DTXSID001003413

Synonyms:83409-17-0;Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3-(4H)-quinazolinyl)butyl)-4-(4-methylphenyl)-;DTXSID001003413;C33H38O5;C33-H38-O5;LS-112910;3-{3-Methyl-1-[4-(4-methylphenyl)piperazin-1-yl]-1-oxobutan-2-yl}-2-(3,4,5-trimethoxyphenyl)quinazolin-4(3H)-one

Suppliers and Price of Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3-(4H)-quinazolinyl)butyl)-4-(4-methylphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3-(4H)-quinazolinyl)butyl)-4-(4-methylphenyl)-

Chemical Property:

Vapor Pressure:2.97E-22mmHg at 25°C
Boiling Point:748°Cat760mmHg
Flash Point:406.2°C
Density:1.22g/cm³
XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:570.28422033
Heavy Atom Count:42
Complexity:944

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2CCN(CC2)C(=O)C(C(C)C)N3C(=NC4=CC=CC=C4C3=O)C5=CC(=C(C(=C5)OC)OC)OC

Technology Process of Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3-(4H)-quinazolinyl)butyl)-4-(4-methylphenyl)-

There total 4 articles about Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3-(4H)-quinazolinyl)butyl)-4-(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 39593-08-3
(4-methylphenyl)piperazine

: 83409-26-1
3-Methyl-2-[4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-butyryl chloride

: 83409-17-0
3-[2-Methyl-1-(4-p-tolyl-piperazine-1-carbonyl)-propyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: In benzene; for 2h; Heating;

Reference yield:

: 40728-74-3
2-(3,4,5-trimethoxyphenyl)-4-H-benzo[d][1,3]oxazin-4-one

: 83409-17-0
3-[2-Methyl-1-(4-p-tolyl-piperazine-1-carbonyl)-propyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / pyridine; H₂O / 10 h / Heating

2: SOCl₂ / benzene / 6 h / Heating

3: 68 percent / benzene / 2 h / Heating

With thionyl chloride; In pyridine; water; benzene;

Reference yield:

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 83409-17-0
3-[2-Methyl-1-(4-p-tolyl-piperazine-1-carbonyl)-propyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 1) 0-5 deg C 2) 1h, room temperature

2: 70 percent / pyridine; H₂O / 10 h / Heating

3: SOCl₂ / benzene / 6 h / Heating

4: 68 percent / benzene / 2 h / Heating

With pyridine; thionyl chloride; In pyridine; water; benzene;