2-(2-Chloro-1-hydroxy-1-methylethyl)-1,2-dihydro-10-hydroxy-5-methoxy-6H-furo(2,3-c)xanthen-6-one

Base Information

Chemical Name:2-(2-Chloro-1-hydroxy-1-methylethyl)-1,2-dihydro-10-hydroxy-5-methoxy-6H-furo(2,3-c)xanthen-6-one
CAS No.:74046-00-7
Molecular Formula:C₁₉H₁₇ClO₆
Molecular Weight:376.793
Hs Code.:
DSSTox Substance ID:DTXSID20995464
Mol file:74046-00-7.mol

Synonyms:3',4'-deoxypsorospermin-4'-chloro-3'-ol;DPCO

Suppliers and Price of 2-(2-Chloro-1-hydroxy-1-methylethyl)-1,2-dihydro-10-hydroxy-5-methoxy-6H-furo(2,3-c)xanthen-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(2-Chloro-1-hydroxy-1-methylethyl)-1,2-dihydro-10-hydroxy-5-methoxy-6H-furo(2,3-c)xanthen-6-one

Chemical Property:

Vapor Pressure:2.21E-16mmHg at 25°C
Melting Point:270 - 272 °C
Boiling Point:623°C at 760 mmHg
Flash Point:330.6°C
PSA：89.13000
Density:1.478g/cm³
LogP:2.95370
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:376.0713660
Heavy Atom Count:26
Complexity:558

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CCl)(C1CC2=C3C(=C(C=C2O1)OC)C(=O)C4=C(O3)C(=CC=C4)O)O
Isomeric SMILES:C[C@](CCl)([C@@H]1CC2=C3C(=C(C=C2O1)OC)C(=O)C4=C(O3)C(=CC=C4)O)O

Technology Process of 2-(2-Chloro-1-hydroxy-1-methylethyl)-1,2-dihydro-10-hydroxy-5-methoxy-6H-furo(2,3-c)xanthen-6-one

There total 3 articles about 2-(2-Chloro-1-hydroxy-1-methylethyl)-1,2-dihydro-10-hydroxy-5-methoxy-6H-furo(2,3-c)xanthen-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 74045-97-9
psorospermin

: 74046-00-7
3',4'-deoxy-4'-chloropsorospermin-3'-ol

Guidance literature:: With hydrogenchloride; In methanol; chloroform; for 2.5h; Ambient temperature;
DOI:10.1021/jo00379a018

Reference yield:

: 106212-05-9
3',4'-deoxypsorospermin-3',4'-diol

: 74046-00-7
3',4'-deoxy-4'-chloropsorospermin-3'-ol

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 1.) 0 deg C, 4 h, 2.) RT, overnight

2: t-BuOK / 2-methyl-propan-2-ol / 1 h / 40 °C

3: 84 percent / conc. HCl / methanol; CHCl₃ / 2.5 h / Ambient temperature

With pyridine; hydrogenchloride; potassium tert-butylate; In methanol; chloroform; tert-butyl alcohol;
DOI:10.1021/jo00379a018

Reference yield:

: Methanesulfonic acid (R)-2-hydroxy-2-((R)-10-hydroxy-5-methoxy-6-oxo-1,2-dihydro-6H-3,11-dioxa-cyclopenta[a]anthracen-2-yl)-propyl ester

: 74046-00-7
3',4'-deoxy-4'-chloropsorospermin-3'-ol

Guidance literature:: Multi-step reaction with 2 steps

1: t-BuOK / 2-methyl-propan-2-ol / 1 h / 40 °C

2: 84 percent / conc. HCl / methanol; CHCl₃ / 2.5 h / Ambient temperature

With hydrogenchloride; potassium tert-butylate; In methanol; chloroform; tert-butyl alcohol;
DOI:10.1021/jo00379a018