N(6)-aminohexyl-flavin adenine dinucleotide

Base Information

• Chemical Name: N(6)-aminohexyl-flavin adenine dinucleotide
• CAS No.: 76748-73-7
• Molecular Formula: C₃₃H₄₆N₁₀O₁₅P₂
• Molecular Weight: 884.734
• Mol file: 76748-73-7.mol

Synonyms:Benzo[g]pteridine,riboflavin 5'-(trihydrogen diphosphate) deriv.; Flavin N6-(6-aminohexyl)adeninedinucleotide; N6-(6-Aminohexyl)-FAD

Chemical Property of N(6)-aminohexyl-flavin adenine dinucleotide

Chemical Property:

• PSA: 400.50000
• LogP: 0.99270

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N6-(6-Aminohexyl)-FAD, is a derivative of Flavine Adenine

Technology Process of N(6)-aminohexyl-flavin adenine dinucleotide

There total 2 articles about N(6)-aminohexyl-flavin adenine dinucleotide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N6-(trifluoroacetamidohexyl)adenosine 5'-monophosphate (66060-76-2) → N6-(6-aminohexyl)adenine dinucleotide (76748-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1: tri.n.butylamine / dimethylformamide / 1.5 h

2: 1.tri-n-octylamine 2.aq.NaOH / 1.DMF, room temp., overnight 2.H₂O, room temp., 9h

With sodium hydroxide; Tri-n-octylamine; tributyl-amine; In N,N-dimethyl-formamide;

DOI:10.1021/ac00227a021

Reference yield:

riboflavin 5'-monophosphate (34469-63-1,69680-01-9) + N6-(trifluoroacetamidohexyl)adenosine 5'-monophosphate imidazolide → N6-(6-aminohexyl)adenine dinucleotide (76748-73-7)

Guidance literature:

With sodium hydroxide; Tri-n-octylamine; Yield given. Multistep reaction; 1.DMF, room temp., overnight 2.H₂O, room temp., 9h;

DOI:10.1021/ac00227a021

upstream raw materials:

riboflavin 5'-monophosphate

N⁶-(trifluoroacetamidohexyl)adenosine 5'-monophosphate

Refernces